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2-(2-Aminothiazol-4-yl)acetic acid

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Identification
Molecular formula
C5H6N2O2S
CAS number
17052-20-9
IUPAC name
2-(2-aminothiazol-4-yl)acetic acid
State
State

At room temperature, 2-(2-Aminothiazol-4-yl)acetic acid exists as a solid. It is stable under normal conditions, although it should be kept in a tightly closed container to prevent it from absorbing moisture.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
158.18g/mol
Molar mass
158.1840g/mol
Density
1.5549g/cm3
Appearence

2-(2-Aminothiazol-4-yl)acetic acid typically appears as a light-colored crystalline solid. It is often a white to off-white powder that may absorb moisture from the air, exhibiting hygroscopic properties.

Comment on solubility

Solubility of 2-(2-aminothiazol-4-yl)acetic acid

2-(2-aminothiazol-4-yl)acetic acid, often noted for its intriguing properties, showcases a distinct solubility profile that is critical for its applications in various fields. Understanding its solubility can be broken down into several key aspects:

  • Aqueous solubility: The compound is generally soluble in water due to the presence of polar functional groups. These polar interactions facilitate its dissolution and allow it to interact with surrounding molecules in aqueous environments.
  • Solvent dependency: Apart from water, 2-(2-aminothiazol-4-yl)acetic acid’s solubility may vary significantly in organic solvents. It is imperative to consider factors like polarity and pH of the solvent, as they can dramatically affect its solubility.
  • Temperature influence: As with many compounds, solubility tends to increase with temperature. This relationship is critical when considering reaction conditions in both laboratory and industrial settings.
  • Ionic strength: The presence of salts or other ionic species in solution can alter the solubility of this compound, either enhancing it or leading to precipitation depending on the ionic interactions.

In summary, the solubility of 2-(2-aminothiazol-4-yl)acetic acid is influenced by a variety of factors, including temperature, pH, and the nature of the solvent used. It is essential to conduct thorough experiments to determine the optimal conditions for solubility in practical applications.

Interesting facts

Interesting Facts about 2-(2-Aminothiazol-4-yl)acetic Acid

2-(2-Aminothiazol-4-yl)acetic acid is a fascinating compound with significant implications in the fields of medicinal chemistry and pharmaceuticals. Here are some intriguing aspects of this compound:

  • Biological Importance: This compound is known for its potential biological activities, notably in antimicrobial and antifungal properties, making it a valuable candidate for drug development.
  • Thiazole Ring: The thiazole moiety, which is part of its structure, is a five-membered ring containing sulfur and nitrogen, and is commonly found in various bioactive compounds.
  • Versatile Synthesis: The synthetic pathways leading to 2-(2-aminothiazol-4-yl)acetic acid are rich and varied, providing opportunities for chemical experimentation and optimization in organic synthesis.
  • Potential Therapeutic Uses: Research indicates that derivatives of this compound could be developed for treating conditions such as bacterial infections, contributing significantly to public health.
  • Research Applications: Its unique structure allows it to be a target for various pharmacological studies, which can help to elucidate mechanisms of action in related compounds.

Furthermore, understanding compounds like 2-(2-aminothiazol-4-yl)acetic acid invites deeper exploration into how molecular architecture affects biological activity. As stated by a prominent chemist, "The beauty of chemistry lies in the details of molecular design and the potential it holds for innovation." This compound exemplifies that principle perfectly.

In summary, 2-(2-aminothiazol-4-yl)acetic acid is not just a structural formula; it represents a gateway to numerous scientific discoveries and advancements in medicine.

Synonyms
(2-Amino-1,3-thiazol-4-yl)acetic acid
RefChem:465225
29676-71-9
2-AMINO-4-THIAZOLEACETIC ACID
2-(2-Aminothiazol-4-yl)acetic acid
2-Aminothiazol-4-acetic acid
4-Thiazoleacetic acid, 2-amino-
(2-Aminothiazole-4-yl)acetic acid
2-(2-amino-1,3-thiazol-4-yl)acetic acid
2-Aminothiazole-4-acetic acid
(2-Amino-4-thiazolyl)acetic acid
MFCD00010068
2-AMINOTHIAZOL-4-YLACETIC ACID
QSH3O4TNJT
CHEMBL71460
2-amino-4-thiazole acetic acid
DTXSID0024509
(2-Aminothiazole-4-YL)-Acetic Acid
2-(2-Aminothiazol-4-yl) acetic acid
UNII-QSH3O4TNJT
EINECS 249-769-6
Mirabegron Impurity 9
NCGC00091091-01
2-Amino-4-thiazoleaceticacid
2-Amino-4-thiazoleaetic acid
SCHEMBL909845
DTXCID004509
SCHEMBL11336052
2-aminothiazol-4-yl-acetic acid
(2-aminothiazol-4-yl)acetic acid
ALBB-021297
BCP12035
2-(2-Aminothiazol-4-yl)aceticacid
Tox21_200900
BBL008947
BDBM50525196
SBB003994
SQ-272
STK711165
(2-amino-thiazol-4-yl)-acetic acid
2-Amino-4-thiazoleacetic acid, 95%
AKOS005207187
AC-5554
FA00978
FS-3431
SB12894
2-(2-Aminothiazole-4-Yl) Acetic Acid
AMINO-4-THIAZOLACETIC ACID, 2-
NCGC00091091-02
NCGC00258454-01
BP-10726
SY019218
CAS-29676-71-9
DB-047623
(2-Amino-1,3-thiazol-4-yl)acetic acid #
2-(2-AMINO-4-THIAZOLYL)ACETIC ACID
A0954
CS-0011440
NS00028746
ST50307902
EN300-30968
76A719
D72492
F093527
Q27287479
F2191-0180