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Pinacidil

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Identification
Molecular formula
C13H19N3
CAS number
51052-80-3
IUPAC name
2-[2-(azocan-1-yl)ethyl]guanidine
State
State

At room temperature, Pinacidil is typically a solid. As with many pharmaceutical compounds, its solid form makes it easier to handle when used in clinical and laboratory settings.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
567.70
Boiling point (Kelvin)
840.85
General information
Molecular weight
211.31g/mol
Molar mass
211.3500g/mol
Density
1.0240g/cm3
Appearence

Pinacidil is typically found in its crystalline form. It appears as white to almost white crystals that are often used in pharmacological applications. Its crystalline appearance is common for many pharmaceutical compounds, making it easily distinguishable in pure form.

Comment on solubility

Solubility of 2-[2-(azocan-1-yl)ethyl]guanidine

The compound 2-[2-(azocan-1-yl)ethyl]guanidine (C13H19N3) exhibits interesting solubility behavior due to its unique molecular structure. Solubility is influenced by various factors, and understanding them is essential for practical applications. Here are some key points regarding its solubility:

  • Polarity: The presence of guanidine functional groups, along with nitrogen atoms, contributes to its polar nature. This may enhance solubility in polar solvents such as water.
  • Hydrogen bonding: The ability to form hydrogen bonds can significantly increase solubility in aqueous environments; thus, compounds containing guanidinium groups are often more soluble in polar solvents.
  • Hydrophobic interactions: The azocan moiety introduces a hydrophobic character, which can affect solubility. As a result, 2-[2-(azocan-1-yl)ethyl]guanidine may show variable solubility depending on the solvent system used.
  • Solvent effects: It may be soluble in organic solvents (e.g., ethanol, methanol) while also retaining a degree of solubility in water.

In conclusion, the solubility of 2-[2-(azocan-1-yl)ethyl]guanidine is determined by its molecular interactions, polarity, and the chemical environment. Thus, it highlights the importance of selecting appropriate solvents for dissolution and applications in various chemical contexts.

Interesting facts

Interesting Facts about 2-[2-(azocan-1-yl)ethyl]guanidine

2-[2-(azocan-1-yl)ethyl]guanidine is a fascinating compound that showcases the incredible diversity of chemical structures and their potential applications. This compound can be broken down into several notable features:

  • Potential Biological Activity: The presence of the guanidine group suggests that this compound may exhibit activity relevant in biological systems. Guanidines are often implicated in the enhancement of enzyme activity and may play roles in various biological processes.
  • Azo Group Influence: The azocan moiety in the compound may impart specific properties such as unique electronic characteristics. Azo compounds are known for their applications in dye chemistry, and they can exhibit interesting photochemical properties.
  • Pharmaceutical Interest: Compounds similar to 2-[2-(azocan-1-yl)ethyl]guanidine could serve as lead compounds in drug design, especially within the realm of targeting specific receptors or pathways in the body.
  • Chirality and Stereochemistry: The presence of asymmetric centers can lead to stereoisomerism, which is a critical aspect to consider in drug development, as different isomers can have vastly different biological activities.

Furthermore, the synthesis and manipulation of 2-[2-(azocan-1-yl)ethyl]guanidine offer substantial opportunities for chemists interested in organic synthesis and material science. As we explore this compound, it remains essential to unlock its full potential through research and application development.

In conclusion, 2-[2-(azocan-1-yl)ethyl]guanidine is not just another organic molecule, but a promising compound that could hold the key to new therapeutic avenues and advanced materials.

Synonyms
GUANETHIDINE
55-65-2
Ismelin
Oktadin
Abapresin
Sanotensin
Eutensol
Octadine
Octatensine
Oktatensin
Oktatenzin
Guanetidina
Dopam
Dopom
Guanethidinum
Octatensin
Isobarin
2-(1'-Azacyclooctyl)ethylguanidine
guanethidine sulfate
Guanidine, (2-(hexahydro-1(2H)-azocinyl)ethyl)-
N-(2-Perhydroazocin-1-ylethyl)guanidine
Azocine, 1-(2-guanidinoethyl)octahydro-
2-(1-N,N-Heptamethyleneimino)ethylguanidine
(2-(Octahydro-1-azocinyl)ethyl)guanidine
1-[2-(azocan-1-yl)ethyl]guanidine
Heptamethylenimine, 1-(2-guanidinoethyl)-
Octadin
2-[2-(azocan-1-yl)ethyl]guanidine
HSDB 3092
1-(2-azocan-1-ylethyl)guanidine
UNII-ZTI6C33Q2Q
EINECS 200-241-3
ZTI6C33Q2Q
Iporal
Guanethidine (INN)
CHEBI:5557
Guanetidin sulfate
Azocine, 1-((2-(aminoiminomethyl)amino)ethyl)octahydro-
DTXSID5023116
(2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine
1-(2-(Azocan-1-yl)ethyl)guanidine
Su 5864 sulfate (1:1)
[2-(Octahydro-1-azocinyl)ethyl]guanidine
GUANETHIDINE [INN]
Guanethidine [INN:BAN]
Guanidine, [2-(hexahydro-1(2H)-azocinyl)ethyl]-
Guanethidinum [INN-Latin]
Guanetidina [INN-Spanish]
NSC29863
[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine
CAS-60-02-6
NCGC00016272-01
((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
Azocine, 1-[[2-(aminoiminomethyl)amino]ethyl]octahydro-
Octatenzine
3h-guanethidine
Iporal (Salt/Mix)
Isobarin (Salt/Mix)
SU 5864
Spectrum_000837
Prestwick0_000317
Prestwick1_000317
Prestwick2_000317
Prestwick3_000317
Spectrum2_001103
Spectrum3_000446
Spectrum4_000568
Spectrum5_000784
GUANETHIDINE [MI]
CHEMBL765
GUANETHIDINE [HSDB]
GUANETHIDINE [VANDF]
SCHEMBL34753
BSPBio_000314
BSPBio_002092
KBioGR_000976
KBioSS_001317
SU 5864 (Salt/Mix)
DivK1c_000539
GUANETHIDINE [WHO-DD]
SPBio_001206
SPBio_002533
BPBio1_000346
DTXCID203116
GTPL7194
KBio1_000539
KBio2_001317
KBio2_003885
KBio2_006453
KBio3_001312
C02CC02
S01EX01
NINDS_000539
HY-B1251
STR07524
.Beta.-1-Azacyclooctylethylguanidine
N-[2-(azocan-1-yl)ethyl]guanidine
STK895063
AKOS005614041
N-[2-(1-Azocanyl)ethyl]guanidine #
CCG-213488
DB01170
IDI1_000539
N''-[2-(azocan-1-yl)ethyl]guanidine
NCGC00016272-02
NCGC00016272-03
NCGC00247765-01
SBI-0051399.P003
AB00053479
CS-0013044
NS00001475
C07036
D08030
EN300-123310
AB00053479_04
AB00053479_05
L000732
Q420673
BRD-K62676709-001-01-9
BRD-K62676709-065-05-5
Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-
Z1198152903
200-241-3