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Identification
Molecular formula
C15H12ClNO4
CAS number
58168-08-2
IUPAC name
2-(2-benzamido-4-chloro-phenoxy)acetic acid
State
State

At room temperature, 2-(2-benzamido-4-chloro-phenoxy)acetic acid is stable and found in a solid state. Its exact appearance may vary based on processing but typically is a fine crystalline or powdered solid.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
535.70
Boiling point (Kelvin)
808.85
General information
Molecular weight
361.72g/mol
Molar mass
361.7960g/mol
Density
1.3957g/cm3
Appearence

The compound 2-(2-benzamido-4-chloro-phenoxy)acetic acid typically appears as a pale yellow to brown solid. It may be available in various forms such as crystals or powder, depending on the specific preparation and purity.

Comment on solubility

Solubility Insights for 2-(2-benzamido-4-chloro-phenoxy)acetic acid

2-(2-benzamido-4-chloro-phenoxy)acetic acid, a compound with both hydrophilic and hydrophobic characteristics, exhibits interesting solubility properties:

  • Aqueous Solubility: This compound is expected to have moderate solubility in water due to the presence of carboxylic acid groups which can ionize.
  • Solubility in Organic Solvents: It is likely to be more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) because of its aromatic structure.
  • pH Dependence: The solubility may vary with pH changes; the acidic form might be more soluble at lower pH compared to its neutral form.

In general, compounds that contain both polar and non-polar functional groups tend to have unique solubility profiles. One could say that "the solubility is influenced by the balance of forces between the solvent and solute." Understanding these solubility characteristics is essential for applications in pharmaceuticals and other chemical formulations where proper dissolution is crucial for efficacy.


Interesting facts

Interesting Facts about 2-(2-benzamido-4-chloro-phenoxy)acetic acid

2-(2-benzamido-4-chloro-phenoxy)acetic acid is a fascinating organic compound that belongs to the class of aromatic carboxylic acids. Here are some intriguing insights into this compound:

  • Biological Activity: This compound is known for its potential biological activity, particularly in the field of pharmaceuticals. It has been investigated for its anti-inflammatory and antimicrobial properties.
  • Pharmacological Interest: Researchers are interested in this compound due to its structural similarity to various drugs, which can lead to novel therapeutic applications. Its unique functional groups allow it to interact with different biological targets.
  • Synthesis: The synthesis of 2-(2-benzamido-4-chloro-phenoxy)acetic acid involves complex organic reactions. Scientists often use methods such as coupling reactions and substitution reactions to construct this compound efficiently.
  • Industrial Applications: Beyond its medicinal properties, this compound may also have applications in the agricultural industry, where it could be potential lead for developing new herbicides or pesticides.
  • Research Trends: Recent studies have focused on the structure-activity relationship (SAR) of this compound, attempting to modify its structure to enhance efficacy and reduce toxicity. This underscores the significance of chemical modifications in drug design.

In summary, 2-(2-benzamido-4-chloro-phenoxy)acetic acid embodies the intersection of organic chemistry and medicinal research. Its continuing exploration could contribute significantly to the advancement of therapeutics and agrochemicals.

Synonyms
BRN 2392975
(2-Benzamido-4-chlorophenoxy)acetic acid
6239-09-4
ACETIC ACID, (2-BENZAMIDO-4-CHLOROPHENOXY)-
2-(2-benzamido-4-chlorophenoxy)acetic acid
DTXSID60977946
(4-Chloro-2-{[hydroxy(phenyl)methylidene]amino}phenoxy)acetic acid