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Benzydamine Hydrochloride

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Identification
Molecular formula
C19H24ClN3O
CAS number
132-69-4
IUPAC name
2-(2-benzhydryl-2-methyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride
State
State

Benzydamine hydrochloride is typically a solid at room temperature. It is stable under normal conditions and should be stored in a cool, dry place to maintain its efficacy and shelf life. The compound is generally kept in closed containers to avoid contamination and degradation.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
246.00
Boiling point (Kelvin)
519.15
General information
Molecular weight
340.89g/mol
Molar mass
340.8880g/mol
Density
1.1500g/cm3
Appearence

Benzydamine hydrochloride appears as a white or almost white crystalline powder. It is odorless or nearly odorless and has a slightly bitter taste. The appearance can vary depending on the purity and specific form, but it is generally uniform in its crystalline structure.

Comment on solubility

Solubility of 2-(2-benzhydryl-2-methyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride

The solubility of 2-(2-benzhydryl-2-methyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride can be examined by considering a number of factors:

  • Polarity: This compound features both a piperidinium moiety and a dioxolane ring. The piperidinium part is generally polar due to the positive charge on the nitrogen, which can lead to good solubility in polar solvents.
  • Functional Groups: The functional groups, particularly the dioxolane, contribute to its solubility behavior. The presence of multiple oxygen atoms can enhance interactions with solvent molecules, making it more soluble in hydrophilic environments.
  • Solvent Interaction: As a quaternary ammonium salt, this compound is expected to be soluble in water and other polar solvents. Solubility in organic solvents might be lower, but it could vary based on the solvent's properties.

In general, quaternary ammonium salts tend to exhibit higher solubility in water due to their ionic nature, making 2-(2-benzhydryl-2-methyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride potentially quite soluble in polar solvents. However, the specific solubility can be influenced by:

  1. Temperature: An increase in temperature typically enhances solubility.
  2. pH: Variations in pH may affect the ionization of the compound.
  3. Concentration: As the concentration of the compound increases, it may reach saturation, impacting solubility further.

Overall, while one might anticipate a significant solubility in polar solvents due to the ionic and polar characteristics of the compound, specific empirical data would be required to confirm this behavior under various conditions.

Interesting facts

Interesting Facts About 2-(2-benzhydryl-2-methyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride

This intriguing compound presents a fascinating blend of functionalities, which could lead to a variety of applications in medicinal chemistry and materials science. Here are some notable facts:

  • Diverse Structure: The presence of a piperidinium moiety suggests potential behavior as a positively charged ion, which can play a crucial role in drug formulation.
  • Stability: The dioxolane ring, comprising two oxygen atoms, adds stability to the structure and can influence the compound's reactivity and interaction properties.
  • Biological Potential: Due to its complex structure, this compound may exhibit interesting pharmacological properties, potentially acting as a lead compound for the development of new therapeutics.
  • Chloride Ion: The presence of the chloride ion indicates that this compound may also be soluble in various solvents, facilitating diverse applications in organic synthesis.
  • Research Interest: The unique combination of benzhydryl and piperidin-1-ium groups may offer insights into structure-activity relationships (SAR) in medicinal chemistry, which is key for designing effective drugs.

Applications in Various Fields

Given its unique structure, 2-(2-benzhydryl-2-methyl-1,3-dioxolan-4-yl)piperidin-1-ium;chloride may find applications in:

  • As a pharmacological agent in neurology and psychiatry.
  • In synthesis laboratories for the production of more complex organic compounds.
  • In studies targeting ion transport mechanisms in cellular systems.

As researchers continue to explore the biochemical pathways influenced by similar compounds, the potential discoveries may lead to groundbreaking advances in drug development and molecular biology. Overall, this compound exemplifies the intersection of structure and function crucial for advancement in various branches of chemistry.

Synonyms
beta-2-Diphenylmethyl-2-methyl-4-(2-piperidyl)-1,3-dioxolane hydrochloride
1,3-DIOXOLANE, 2-DIPHENYLMETHYL-2-METHYL-4-(2-PIPERIDYL)-, HYDROCHLORIDE, beta-
3666-73-7