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Telmisartan

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Identification
Molecular formula
C33H30N4O2
CAS number
144701-48-4
IUPAC name
2-(2-benzylbenzimidazol-1-yl)-N,N-dimethyl-propan-1-amine
State
State
Telmisartan is typically found as a solid at room temperature.
Melting point (Celsius)
261.00
Melting point (Kelvin)
534.15
Boiling point (Celsius)
403.00
Boiling point (Kelvin)
676.15
General information
Molecular weight
514.63g/mol
Molar mass
514.6340g/mol
Density
1.1064g/cm3
Appearence

Telmisartan appears as a white to slightly yellowish crystalline powder. It is practically insoluble in water but soluble in strong acid or base solutions.

Comment on solubility

Solubility of 2-(2-benzylbenzimidazol-1-yl)-N,N-dimethyl-propan-1-amine

The solubility of 2-(2-benzylbenzimidazol-1-yl)-N,N-dimethyl-propan-1-amine can be influenced by several factors, making it a compound of particular interest in chemical investigations.

Key Factors Impacting Solubility:

  • Molecular Structure: The presence of the benzyl and benzimidazole groups can enhance the molecular interactions with solvents, potentially leading to increased solubility in organic media.
  • Polarity: The balance between hydrophilic and hydrophobic segments in the molecule determines its solubility in polar vs. non-polar solvents. This compound may exhibit different solubility characteristics depending on the solvent used.
  • Temperature: As with many chemical compounds, solubility can vary significantly with temperature, often increasing with rising temperatures.

In practice, one might observe that this particular compound has limited solubility in water, a common trait for many organic compounds, while being more soluble in organic solvents such as dichloromethane or ethanol.

Understanding the solubility profile of this compound not only assists in practical applications but also provides insights into the underlying molecular interactions at play. In summary, when evaluating solubility, one should consider a variety of environmental conditions and solvent options to determine the most effective medium for application.

Interesting facts

Interesting Facts about 2-(2-benzylbenzimidazol-1-yl)-N,N-dimethyl-propan-1-amine

This compound, 2-(2-benzylbenzimidazol-1-yl)-N,N-dimethyl-propan-1-amine, demonstrates intriguing qualities that are worthy of exploration within the realms of medicinal chemistry and pharmacology. Here are some fascinating aspects:

  • Structure Diversity: The presence of the benzimidazole moiety in this compound highlights its potential as a biologically active scaffold. Benzimidazoles are known for their diverse pharmacological activities, which can include anticancer, antiviral, and antifungal properties.
  • Biological Applications: Research has indicated that compounds containing the benzyl group linked to a benzimidazole can exhibit notable biological activities, making them promising candidates for drug development.
  • Pharmacophoric Elements: The inclusion of the N,N-dimethyl functional group contributes to enhancing solubility and bioavailability, significant factors that pharmaceutical chemists consider during drug design.
  • Molecular Interactions: The ability of this compound to form various interactions, such as hydrogen bonding and π-π stacking due to its aromatic components, can play a critical role in binding to biological targets.

"The chemistry behind drug discovery is just as thrilling as the end results themselves." This statement resonates particularly well with the exploratory nature of compounds like 2-(2-benzylbenzimidazol-1-yl)-N,N-dimethyl-propan-1-amine, where structural modifications can lead to new therapeutic agents.

As ongoing research unfolds, this compound may contribute valuable insights and advancements in numerous therapeutic areas. Its multifaceted structure and the inherent properties of its components illustrate the endless possibilities that exist in the world of chemical compounds.