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Benzydamine Hydrochloride

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Identification
Molecular formula
C26H32NO4S
CAS number
52663-81-7
IUPAC name
[2-(2-benzylphenoxy)-1-methyl-ethyl]-trimethyl-ammonium;4-methylbenzenesulfonate
State
State

Benzydamine is typically found as a solid at room temperature, either in powder or crystalline form, especially when supplied as its salt forms for pharmaceutical use.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
441.61g/mol
Molar mass
441.6000g/mol
Density
1.2000g/cm3
Appearence

Benzydamine is generally available as a white crystalline powder or in crystalline form. When it forms salts, such as benzydamine hydrochloride, it appears as a fine white crystalline substance. As a pharmaceutical substance, it often appears in solution for topical use.

Comment on solubility

Solubility of [2-(2-benzylphenoxy)-1-methyl-ethyl]-trimethyl-ammonium;4-methylbenzenesulfonate

The solubility of the compound [2-(2-benzylphenoxy)-1-methyl-ethyl]-trimethyl-ammonium;4-methylbenzenesulfonate can be considered in the context of its ionic and polar characteristics. Given its quaternary ammonium structure, this compound exhibits several notable solubility features:

  • High Solubility in Polar Solvents: Compounds with quaternary ammonium groups tend to be highly soluble in water and other polar solvents due to the presence of charged species that interact favorably with polar solvent molecules.
  • Limited Solubility in Non-Polar Solvents: Conversely, this compound is likely to have low solubility in non-polar solvents such as hydrocarbons, reflecting the principle of like dissolves like.
  • Influence of Counterions: The presence of the 4-methylbenzenesulfonate counterion can enhance the solubility in aqueous solutions, as sulfonate groups are known to contribute to ionic strength and solubility.

Overall, one can anticipate that under typical conditions, this compound will exhibit significant solubility in aqueous environments and polar organic solvents, making it versatile in various chemical applications.

Interesting facts

Interesting Facts about [2-(2-benzylphenoxy)-1-methyl-ethyl]-trimethyl-ammonium;4-methylbenzenesulfonate

This compound, known for its complex structure, presents several fascinating characteristics that highlight its importance in the field of chemistry. Here are some key points to consider:

  • Pharmaceutical Applications: This compound plays a significant role in medicinal chemistry. Compounds that incorporate quaternary ammonium salts often exhibit antimicrobial properties, making them essential in the development of antiseptics and disinfectants.
  • Structure-Activity Relationship: The unique combination of a benzyl group and a sulfonate group in this compound allows researchers to explore how structural variations can influence biological activity.
  • Ion Pairing: The presence of the quaternary ammonium component enhances its solubility and ionic character, enabling interesting studies in ion-pairing phenomena, particularly in electrolytic solutions.
  • Solvent Effects: This compound can serve as a model for understanding how solvents can affect the reactivity and stability of ionic compounds, which is vital for applications in organic synthesis.
  • Research Potential: With ongoing research in green chemistry, exploring the synthesis and use of this compound could lead to more sustainable and environmentally friendly approaches to chemical production.

In summary, [2-(2-benzylphenoxy)-1-methyl-ethyl]-trimethyl-ammonium;4-methylbenzenesulfonate exemplifies the intricate relationship between molecular structure and functionality. As noted by leading chemists, "The beauty of chemistry lies in the endless possibilities the molecular world offers us." This compound is a testament to that possibility and its potential for future advancements.

Synonyms
7347-92-4
(1-((2-Benzylphenoxy)methyl)ethyl)trimethylammonium toluenesulfonate
AMMONIUM, (1-((2-BENZYLPHENOXY)METHYL)ETHYL)TRIMETHYL-, TOLUENESULFONATE
DTXSID10994229
1-(2-Benzylphenoxy)-N,N,N-trimethylpropan-2-aminium 4-methylbenzene-1-sulfonate