Skip to main content

Adefovir

ADVERTISEMENT
Identification
Molecular formula
C18H23N7O4
CAS number
106941-25-7
IUPAC name
2-[[2-[bis(2-hydroxyethyl)amino]-4-(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
State
State

At room temperature, Adefovir is a solid compound.

Melting point (Celsius)
279.00
Melting point (Kelvin)
552.15
Boiling point (Celsius)
511.90
Boiling point (Kelvin)
785.10
General information
Molecular weight
273.26g/mol
Molar mass
273.2580g/mol
Density
1.5809g/cm3
Appearence

Adefovir is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[[2-[bis(2-hydroxyethyl)amino]-4-(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol

The solubility of complex organic compounds, such as 2-[[2-[bis(2-hydroxyethyl)amino]-4-(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, can be influenced by several factors:

  • Polarity: The presence of multiple hydroxyl (-OH) groups in the structure enhances its ability to interact with polar solvents, making it more likely to dissolve in water.
  • Hydrogen Bonding: The functional groups can form extensive hydrogen bonds with solvent molecules, which often leads to increased solubility in aqueous solutions.
  • Temperature: As temperature increases, solubility can often improve for many solid compounds, suggesting that warming the solution might enhance the solubility of this compound.
  • Interactions with Solvents: The compound may show varied solubility in different solvents, with a strong tendency to dissolve in solvents that can adequately stabilize its ionic or polar regions.

It is crucial to note that while high polarity and hydrogen bonding may suggest significant aqueous solubility, experimental data would be necessary to ascertain precise solubility values. Therefore, understanding the compound's behavior in various solvents is key for its practical applications in chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 2-[[2-[bis(2-hydroxyethyl)amino]-4-(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol

This compound is a prime example of the intersection of organic chemistry and pharmacology. With its complex structure, it exhibits fascinating properties that make it a subject of interest in scientific research.

Key Features:

  • Potential Pharmaceutical Applications: The presence of the piperidine ring and the multiple hydroxyethyl amino groups suggest that this compound may be useful in developing therapeutic agents.
  • Structural Complexity: The fused pyrimidine and pyrimidinyl rings showcase an intricate architecture, which is often linked to unique biological activities.
  • Hydrophilic Characteristics: Due to the multiple hydroxyl (–OH) groups, the compound is expected to possess significant hydrophilic properties, which can influence its solubility and interaction with biological systems.
  • Mechanism of Action: Compounds like this one, containing nitrogen-rich cycles, might target specific enzymes or receptors in the body, leading to fascinating pathways of action in treatments.
  • Research Interests: The exploration of similar compounds leads to significant advancements in understanding drug design, making them popular among medicinal chemists.

As Albert Einstein once said, "The important thing is not to stop questioning. Curiosity has its own reason for existence." This compound exemplifies the spirit of inquiry within the scientific community, as researchers continue to explore its potential therapeutic benefits. Given the rising interest in nitrogen-rich heterocycles in medicinal chemistry, studying this compound may unveil new avenues for innovation in drug development.

In summary, 2-[[2-[bis(2-hydroxyethyl)amino]-4-(1-piperidyl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol holds exciting possibilities worth exploring, both for its chemical properties and its prospective applications in medicine.

Synonyms
MOPIDAMOL
13665-88-8
Rapenton
Mopidamolum
RA-233
4Q0IWP8B8O
2,2',2'',2'''-((4-Piperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol
Ethanol, 2,2',2'',2'''-((4-(1-piperidinyl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakis-
DTXSID30159878
DTXCID0082369
2,6-Bis(diethanolamino)-4-piperidino-pyrimido(5,4-d)pyrimidine
2,2',2\",2\"'-((4-Piperidinopyrimido(5,4-d-)pyrimidine-2,6-diyl)dinitrilo)tetraethanol
2,2',2\",2\"'-((4-(1-Piperidinyl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetrakisethanol
237-145-6
RA 233
2-[[2-[bis(2-hydroxyethyl)amino]-4-piperidin-1-ylpyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol
Compound RA-233
Mopidamolum [INN-Latin]
2,2',2'',2'''-((4-(piperidin-1-yl)pyrimido[5,4-d]pyrimidine-2,6-diyl)bis(azanetriyl))tetrakis(ethan-1-ol)
Mopidamol [INN:BAN]
R-A 233-BS
EINECS 237-145-6
UNII-4Q0IWP8B8O
BRN 0587985
MOPIDAMOL [INN]
2,6-Bis(diethanolamino)-4-piperidinopyrimido(5,4-d)pyrimidine
MOPIDAMOL [MI]
MOPIDAMOL [MART.]
MOPIDAMOL [WHO-DD]
SCHEMBL9440
orb1701908
CHEMBL2106769
SCHEMBL29352335
SCHEMBL30179377
CHEBI:135682
FOYWNSCCNCUEPU-UHFFFAOYSA-N
AKOS040747180
2,2',2',2'''-((4-Piperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol
Ethanol, 2,2',2'',2'''-((4-piperidinopyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetra-
TS-08438
HY-106618
CS-0026161
NS00005622
Q27260347