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Chlorhexidine

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Identification
Molecular formula
C22H30Cl2N10O3
CAS number
3697-42-5
IUPAC name
2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium;chloride
State
State

At room temperature, Chlorhexidine in its solid form is a stable crystalline powder. It is usually administered in solution form, particularly in medical and dental applications.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
875.45g/mol
Molar mass
875.4510g/mol
Density
1.0620g/cm3
Appearence

Chlorhexidine appears as a white or almost white crystalline powder. It is characterized by its lack of odor and is typically marketed in its salt forms, which are soluble in water, giving a colorless solution.

Comment on solubility

Solubility of 2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium chloride

The solubility of 2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium chloride in various solvents is of significant interest due to its potential applications. Understanding its solubility characteristics can be crucial in various chemical processes.

Solubility Characteristics:

  • In Water: This compound is expected to exhibit moderate solubility in water due to the presence of the quaternary ammonium group, which typically enhances solubility in polar solvents.
  • In Organic Solvents: It may have better solubility in organic solvents such as ethanol or methanol, which can facilitate interactions with the non-polar segments of the molecule.
  • Solubility Dependence: The solubility can be influenced by factors such as temperature, pH levels, and the presence of salts in solution.

As a general rule, the like dissolves like principle applies. Thus, understanding the balance between hydrophilic and hydrophobic moieties in 2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium chloride is crucial for predicting its solubility behavior. In practical terms, when aiming to dissolve this compound for chemical applications, one may consider a solvent system that combines both polar and non-polar characteristics.

Overall, while specific solubility data might be sparse, the structural features of the compound suggest it could be reasonably soluble in both polar and non-polar solvents depending on the conditions.

Interesting facts

Interesting Facts about 2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium;chloride

The compound 2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium;chloride is a fascinating example of a quaternary ammonium salt with diverse applications and chemical properties.

Key Characteristics

  • Functionality: This compound features a quaternary ammonium group, which often enhances its solubility and interaction with biological membranes, making it of interest in pharmaceuticals and biotechnology.
  • Biological Relevance: The presence of the nitro group is notable; it often plays a significant role in modulating biological activity, potentially impacting its effectiveness in medicinal chemistry.
  • Versatile Applications: It can serve various purposes, including as an antimicrobial agent, surfactant, and in drug formulation, showcasing its multifaceted nature in chemical applications.

Chemical Interactions

This compound's structure suggests the ability to participate in numerous chemical reactions, particularly those involving nucleophiles or electrophiles due to its reactive substituents. The balance of hydrophobic and hydrophilic segments in its molecular structure allows it to interact favorably with both lipid and aqueous environments.

Research Insights

  • Studies often explore the compound's efficacy in disrupting cellular membranes, which is significant in drug delivery systems.
  • Research on its toxicity and environmental impact is ongoing, highlighting the compound's relevance in discussions about safety and sustainability in chemistry.
  • Its ability to enhance drug solubility and bioavailability makes it a topic of great interest in pharmaceutical development.

In summary, 2-(2-butanoyl-6-nitro-phenoxy)ethyl-diethyl-ammonium;chloride exemplifies the intricate relationship between chemical structure and function. Its diverse applications, coupled with its unique properties, make it an exciting subject for continued research and exploration in the field of chemistry.

Synonyms
Butyrophenone, 6'-(2-(diethylamino)ethoxy)-5'-nitro-, hydrochloride
2-Butyryl-6-nitro-beta-(N,N-diethyl)phenoxyethylamine, hydrochloride
BUTYROPHENONE, 2'-(2-(DIETHYLAMINO)ETHOXY)-3'-NITRO-, HYDROCHLORIDE
20809-11-4
RefChem:331365