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Lisinopril

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Identification
Molecular formula
C21H31N3O5
CAS number
76547-98-3
IUPAC name
2-[[2-(carboxymethylamino)-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid
State
State

At room temperature, lisinopril is a solid compound.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
1 004.15
Boiling point (Kelvin)
1 277.30
General information
Molecular weight
405.49g/mol
Molar mass
405.4860g/mol
Density
1.2109g/cm3
Appearence

Lisinopril appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[[2-(carboxymethylamino)-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid

The solubility of the compound 2-[[2-(carboxymethylamino)-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid, with the chemical formula C21H31N3O5, is influenced by several factors due to its complex structure.

  • Hydrophilicity vs. Hydrophobicity: The presence of carboxymethylamino and amino groups contributes to the compound's ability to interact with water, suggesting varying degrees of hydrophilicity.
  • Solvents: This compound is likely to be more soluble in polar solvents like water and methanol, while exhibiting lower solubility in non-polar solvents like hexane.
  • pH Dependency: The solubility can also depend on the pH of the solution, as the ionization of carboxylic acid groups may increase solubility in alkaline conditions.
  • Concentration Effects: As concentration increases, the interactions between molecules can lead to decreased solubility, a phenomenon known as salting out.

Overall, the intricate functionalities of this compound suggest that it exhibits moderate solubility characteristics, making it potentially useful in various applications where solubility plays a crucial role.

Interesting facts

Interesting Facts about 2-[[2-(carboxymethylamino)-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid

This compound is a fascinating example of a synthetic amino acid derivative, known for its complex structure and potential applications in various fields. Here's a closer look at some interesting aspects of this compound:

  • Biochemical Importance: The structural features of this compound, including its amino acid and carboxymethyl groups, suggest that it may play a role in biological systems, possibly influencing metabolic pathways.
  • Potential Therapeutic Uses: Given its unique structure, scientists are exploring its potential uses in drug design, particularly in developing treatments for metabolic disorders.
  • Influence on Protein Structure: Compounds like this can serve as building blocks for creating peptides and proteins, contributing to our understanding of protein folding and stability.
  • Study of Drug Interactions: Researchers may investigate how this compound interacts with various enzymes and receptors, allowing for insights into the mechanisms of action of pharmacological agents.

In the words of renowned chemist Linus Pauling, "The secret of life is not a secret at all, it is a knowledge of the interactions of molecules." The study of compounds such as this highlights the intricate web of interactions that drive biochemical processes in living organisms.

As ongoing research continues to unveil more about this compound, its contributions to science and medicine are likely to expand, making it a subject of interest for both chemists and medical researchers alike.

Synonyms
SCHEMBL17026706
DB-056491