Skip to main content

Diphenylacetic acid

ADVERTISEMENT
Identification
Molecular formula
C14H12O2
CAS number
117-34-0
IUPAC name
2-[2-(carboxymethyl)phenyl]acetic acid
State
State

At room temperature, diphenylacetic acid is in a solid state, typically a crystalline powder.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
198.22g/mol
Molar mass
198.2190g/mol
Density
1.3800g/cm3
Appearence

Diphenylacetic acid is a white crystalline powder. It may form needle-like crystals when precipitated from solution. This compound is typically purer when appearing as clear, white crystals.

Comment on solubility

Solubility of 2-[2-(carboxymethyl)phenyl]acetic acid

The solubility of the compound 2-[2-(carboxymethyl)phenyl]acetic acid, which can also be referred to as *o-Carboxymethylphenylacetic acid*, is an interesting subject due to its multifaceted nature. This compound belongs to the category of carboxylic acids, characterized by functionality that typically enhances solubility in various solvents.

Factors Influencing Solubility

Several factors contribute to the solubility of this compound:

  • Polarity: The presence of carboxylic acid groups increases polarity, facilitating solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules enhances its dissolving capability.
  • Temperature: Increased temperature generally improves solubility as molecular interactions become more dynamic.
  • pH Levels: The ionization of the carboxylic group in different pH environments can significantly alter its solubility.

General Insights

In general, *2-[2-(carboxymethyl)phenyl]acetic acid* exhibits:

  • High solubility in water due to its polar nature.
  • Potentially variable solubility in organic solvents, varying widely based on their polarity.
  • Notable interactions with aqueous solutions that can lead to enhanced dissolution rates.

As stated, "the key to understanding a compound's solubility lies in recognizing the balance of its polar and nonpolar characteristics." Consequently, 2-[2-(carboxymethyl)phenyl]acetic acid, with its unique structure, serves as an excellent example in the study of solubility dynamics in chemistry.

Interesting facts

Interesting Facts about 2-[2-(Carboxymethyl)phenyl]acetic Acid

2-[2-(Carboxymethyl)phenyl]acetic acid, also known as a derivative of phenylacetic acid, is a noteworthy compound in the realm of organic chemistry. Here are some *intriguing details* about this compound:

  • Biological Relevance: This compound has been studied for its potential biological activities, including anti-inflammatory and analgesic properties, making it relevant in pharmaceutical research.
  • Versatility: Its structure allows for the attachment of various functional groups, leading to an array of derivatives that can expand its application in the synthesis of new drugs.
  • Synthesis: The most common method for synthesizing 2-[2-(carboxymethyl)phenyl]acetic acid involves a multi-step process that typically includes the condensation of phenylacetic acid derivatives with carboxymethylating agents.
  • Analytical Techniques: To confirm the identity and purity of this compound, scientists often utilize techniques such as NMR (Nuclear Magnetic Resonance) and IR (Infrared Spectroscopy).
  • Therapeutic Applications: Compounds related to carboxymethylated phenylacetic acids have been explored for their potential use in treating conditions like chronic pain and certain inflammatory diseases.

With its *unique chemical structure* and potential applications, 2-[2-(carboxymethyl)phenyl]acetic acid is just one example of how modifications to simple organic compounds can lead to significant advances in medicinal chemistry.

Synonyms
o-Phenylenediacetic acid
EINECS 231-355-1
DTXSID40225957
NSC 401681
DTXCID70148448
231-355-1
1,2-Phenylenediacetic acid
7500-53-0
2,2'-(1,2-Phenylene)diacetic acid
2-[2-(carboxymethyl)phenyl]acetic acid
1,2-BENZENEDIACETIC ACID
o-Benzenediacetic acid
MFCD00004329
phenylenediacetic acid
o-phenylene-diacetic acid
ortho-phenylenediacetic acid
1,2-phenylene diacetic acid
1.2-phenylene diacetic acid
SCHEMBL30359
CHEMBL347735
MMEDJBFVJUFIDD-UHFFFAOYSA-
1,2-Phenylenediacetic acid, 99%
2,2'-(1,2-Phenylene)diaceticacid
NSC401681
(2-Carboxymethyl-phenyl)-acetic acid
AKOS015915085
CS-W008103
HY-W008103
NSC-401681
PB48771
AC-22736
DS-14576
SY012992
DB-074935
NS00047039
P1052
EN300-114928
P10009
InChI=1/C10H10O4/c11-9(12)5-7-3-1-2-4-8(7)6-10(13)14/h1-4H,5-6H2,(H,11,12)(H,13,14)