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Clomipramine

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Identification
Molecular formula
C19H23ClN2
CAS number
303-49-1
IUPAC name
2-[(2-chloro-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)oxy]ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

Clomipramine is typically in a solid state at room temperature. It is often provided in powdered form or pressed into tablet form for therapeutic use. The solid nature of this compound makes it stable under a variety of conditions, facilitating its use in various pharmaceutical applications.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
314.85g/mol
Molar mass
314.8450g/mol
Density
1.3700g/cm3
Appearence

Clomipramine is typically observed as a crystalline solid. The compound may appear as a white to off-white powder, depending on its purity and form. It may also have a characteristic odor that can be identified under laboratory conditions.

Comment on solubility

Solubility of 2-[(2-chloro-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)oxy]ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound presents an intriguing challenge in terms of solubility. Understanding its solubility properties is essential for its applications in various fields. Here are some key points to consider:

  • Polarity: The presence of both a quaternary ammonium group and a hydroxyl group contributes to a balance of polar and non-polar character, which can influence solubility in various solvents.
  • Solvent Interaction: It may exhibit higher solubility in polar solvents such as water or methanol, while potentially lower in non-polar solvents like hexane.
  • Functional Groups: The functional groups in the compound, particularly the hydroxyl (-OH) and the amine, can form hydrogen bonds, enhancing solubility in polar media.
  • Effect of Temperature: As with many compounds, solubility might increase with temperature, allowing for better dissolution in solvents at elevated temperatures.

In summary, while the solubility of 2-[(2-chloro-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)oxy]ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate is likely influenced by its unique structural characteristics, further experimental investigations would be essential to define precise solubility parameters. As always, it is important to test solubility under varying conditions to gain a comprehensive understanding.


Interesting facts

Interesting Facts about 2-[(2-chloro-5,6-dihydrobenzob[1]benzothiepin-6-yl)oxy]ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound, a member of the quaternary ammonium salts, demonstrates fascinating properties and potential applications. It belongs to a class known for their biological activity, making them of great interest in medicinal chemistry. Here are some noteworthy points:

  • Synthetic Versatility: The integration of the benzo[b][1]benzothiepin moiety suggests that it may exhibit unique pharmacological profiles, potentially influencing its interaction with biological targets.
  • Chlorine Substitution: The presence of chlorine is often associated with increased lipophilicity, which can enhance the permeability of the compound across cellular membranes, a desirable trait in drug design.
  • Role in Antimicrobial Activity: Many quaternary ammonium compounds are well-known for their antimicrobial properties, often utilized as disinfectants or antiseptics. This raises intrigue about the compound's utility in healthcare settings.
  • Potential as a Herbicide: The structure also hints at possibilities for agricultural applications, particularly in the development of new herbicides that could target specific weeds without harming crops.

The versatility of this compound underscores the importance of exploring its mechanistic pathways. As a scientist or student, one might consider performing in vitro studies to elucidate its biological effects, or computational models to predict interactions with various enzymes or receptors.

In conclusion, this compound is an exemplary representation of how chemical structures correlate with biological activity, embodying the intricacies of chemical innovation in both the pharmaceutical and agricultural sciences.