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Amodiaquine

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Identification
Molecular formula
C20H22ClN3O
CAS number
6398-98-7
IUPAC name
2-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yl)oxy]propyl-dimethyl-ammonium;dichloride
State
State
Amodiaquine is a solid at room temperature, typically appearing in its stable crystalline form.
Melting point (Celsius)
202.00
Melting point (Kelvin)
475.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
355.86g/mol
Molar mass
355.8550g/mol
Density
1.3800g/cm3
Appearence

Amodiaquine typically appears as a yellow or brownish-yellow crystalline powder. It may have a slightly bitter taste and is used primarily as an antimalarial agent.

Comment on solubility

Solubility of 2-[(2-chloro-7,8,9,10-tetrahydro-6H-cycloheptabquinolin-5-ium-11-yl)oxy]propyl-dimethyl-ammonium; dichloride

The solubility of 2-[(2-chloro-7,8,9,10-tetrahydro-6H-cycloheptabquinolin-5-ium-11-yl)oxy]propyl-dimethyl-ammonium; dichloride is an interesting topic due to its complex structure and ionic nature. Here are some key points regarding its solubility:

  • Solvent Interaction: This compound tends to exhibit good solubility in polar solvents, primarily due to its quaternary ammonium structure, which allows for favorable interactions with water molecules.
  • Temperature Effect: Like many ionic compounds, solubility may increase with temperature. Higher temperatures generally lead to greater solute solubility.
  • Ion Pairing: In aqueous solutions, ion pairing can affect the overall solubility, especially when competing ions are present.
  • pH Dependency: The solubility can also be influenced by the pH of the solution, as changes in charge on the molecular fragments can result in varying solubility characteristics.

Overall, the solubility of this compound showcases the balance between its hydrophilic and hydrophobic characteristics, making it a suitable subject for further investigation into its potential applications in various fields.

Interesting facts

Interesting Facts about 2-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yl)oxy]propyl-dimethyl-ammonium; dichloride

This fascinating compound holds a prominent place in the field of medicinal chemistry, thanks to its unique structural characteristics and potential applications. Here are some engaging facts about this compound:

  • Complex Structure: The presence of the cyclic structure, including a quinoline moiety, gives rise to intriguing chemical behavior and biological interactions. Its structural intricacies make it a subject of interest in research.
  • Biological Significance: Compounds similar to this one have been studied for their activity against various diseases. The tetrahydroquinoline structure indicates potential antimalarial or anticancer properties, which show promise in pharmacological research.
  • Mechanism of Action: The quaternary ammonium moiety suggests it may function as a neurotransmitter or neuromodulator, influencing synaptic transmission and starting new avenues of investigation.
  • Chlorine Substitution: The substitution of chlorine in this compound may enhance its reactivity and selectivity, a concept of great importance in drug design and development.
  • Quaternary Ammonium Compounds: These compounds are known for various uses, including their application as disinfectants, surfactants, and in drug formulation, indicating this compound might have practical applications beyond simple therapeutic use.

Ultimately, the compound 2-[(2-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-5-ium-11-yl)oxy]propyl-dimethyl-ammonium; dichloride presents numerous exciting possibilities. As the scientific community continues to delve deeper into its properties and reactions, the potential for innovative applications in medicine and chemistry remains vast.

Synonyms
5287-73-0
6H-Cyclohepta(b)quinoline, 2-chloro-11-(2-(dimethylamino)-1-methylethoxy)-7,8,9,10-tetrahydro-, dihydrochloride
6H-Cyclohepta(b)quinoline, 2-chloro-11-(2-(dimethylamino)-1-methylethoxy)- 7,8,9,10-tetrahydro-, dihydrochloride