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2-(2-chloroacetyl)benzonitrile

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Identification
Molecular formula
C9H6ClNO
CAS number
33924-30-2
IUPAC name
2-(2-chloroacetyl)benzonitrile
State
State

At room temperature, 2-(2-chloroacetyl)benzonitrile is typically in a solid state.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
284.30
Boiling point (Kelvin)
557.45
General information
Molecular weight
179.61g/mol
Molar mass
179.6060g/mol
Density
1.2750g/cm3
Appearence

2-(2-Chloroacetyl)benzonitrile is a solid compound that typically appears as a crystalline powder. The exact color may vary from white to light yellow, depending on its purity and preparation method.

Comment on solubility

Solubility of 2-(2-chloroacetyl)benzonitrile

2-(2-chloroacetyl)benzonitrile is known for its intriguing solubility characteristics in various solvents, which can significantly affect its practical applications in chemical processes. Understanding its solubility can be broken down into key points:

  • Polar Solvents: This compound has moderate solubility in polar solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), allowing it to readily interact with polar environments.
  • Non-Polar Solvents: Conversely, it exhibits lower solubility in non-polar solvents like hexane and benzene. This behavior is primarily due to the polar character of the chlorinated acetyl group.
  • Temperature Effects: As with many organic compounds, solubility can be affected by temperature. An increase in temperature often leads to increased solubility as kinetic energy overcomes intermolecular forces.
  • pH Influence: The solubility of 2-(2-chloroacetyl)benzonitrile may also be influenced by the pH of the solvent, particularly in aqueous solutions where ionization can alter solubility dynamics.

In summary, while 2-(2-chloroacetyl)benzonitrile generally displays favorable solubility in certain polar solvents, its performance can vary significantly based on the solvent type and external conditions. The statement, "Like dissolves like," is a motto to remember when considering its solubility profile!

Interesting facts

Exploring 2-(2-chloroacetyl)benzonitrile

2-(2-chloroacetyl)benzonitrile is a fascinating chemical compound that holds significance in both synthetic chemistry and pharmaceutical research. Here are some interesting facts about this compound:

  • Structural Diversity: The compound features a unique combination of a benzonitrile moiety with a chloroacetyl group. This structural diversity can lead to interesting reactivity and interaction patterns.
  • Pharmaceutical Relevance: Compounds that contain nitriles and acyl groups are often studied for their biological activities, making 2-(2-chloroacetyl)benzonitrile a candidate for potential medicinal applications.
  • Reactivity Potential: The presence of the chloroacetyl group suggests that the compound may undergo nucleophilic substitution reactions, which could be useful for further functionalization in synthetic pathways.
  • Applications in Organic Synthesis: This compound can serve as a critical intermediate in the synthesis of a variety of other organic molecules, showcasing its versatility.
  • Analytical Techniques: Researchers often utilize techniques such as NMR spectroscopy and mass spectrometry to characterize compounds like 2-(2-chloroacetyl)benzonitrile, highlighting its unique properties and behaviors.

In summary, 2-(2-chloroacetyl)benzonitrile exemplifies the complexity and utility of organic compounds in scientific research. As a compound that bridges synthetic chemistry and medicinal science, it emphasizes the ongoing interplay between basic research and potential therapeutic applications. As scientists delve deeper into its properties, who knows what other surprises this compound may reveal?

Synonyms
1008-15-7
USAF uctl-668
alpha-Chloro-o-cyanoacetophenone
BENZONITRILE, o-(CHLOROACETYL)-
BRN 2088199
DTXSID10143513
DTXCID8066004
2-(2-chloroacetyl)benzonitrile
Benzonitrile, 2-(2-chloroacetyl)-
Benzonitrile, 2-(Chloroacetyl)- (9Ci)
BENZONITRILE, 2-(CHLOROACETYL)-
DB-274624