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Chlorpromazine

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Identification
Molecular formula
C17H20Cl2N2
CAS number
69-09-0
IUPAC name
2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

At room temperature, chlorpromazine hydrochloride is typically a solid in the form of a crystalline powder.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
319.27g/mol
Molar mass
319.2680g/mol
Density
1.2442g/cm3
Appearence

Chlorpromazine hydrochloride appears as a white or slightly creamy white, crystalline powder that may have a slight, characteristic odor. It is often used in salt form due to increased solubility, which appears as fine crystals.

Comment on solubility

Solubility of 2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride

The solubility of 2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride can be characterized by several key points:

  • Solvent Compatibility: This compound tends to be soluble in polar solvents, particularly water and alcohols, owing to its ionic nature due to the chloride ion.
  • Temperature Dependence: Solubility may increase with temperature, which is common for many ionic compounds.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution, as the presence of acidic or basic conditions may impact the ionization state.
  • General Observations: As a quaternary ammonium salt, it likely exhibits good solubility in aqueous media but may have limited solubility in nonpolar solvents.

In summary, while 2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride is typically soluble in polar solvents, the exact solubility can vary based on temperature and pH conditions, making it essential to consider these factors during its application or synthesis.

Interesting facts

2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride: An Intriguing Compound

This compound, often known in scientific circles for its unique structure and pharmacological potential, is synthesized through the reaction of various precursors. Here are some captivating facts about its properties and significance:

  • Novel Structure: The compound features a tetrahydroisoquinoline framework, which is of great interest due to its role in medicinal chemistry. This core structure is found in many bioactive molecules.
  • Chloride Ion Role: The presence of the chloride ion not only contributes to the compound's overall stability but also may influence its biological activity. Chloride ions often act as counterions that can affect solubility and reactivity.
  • Biological Significance: Compounds of a similar class have been studied for their potential therapeutic effects, including their anti-cancer and anti-inflammatory properties. This makes the exploration of 2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride particularly important.
  • Research Applications: In the lab, this compound may be used as a starting material in the synthesis of other more complex molecules, showcasing its versatility in organic synthesis.
  • Potential for Development: The study of this compound can lead to the discovery of new drugs, as researchers continuously seek out novel compounds for therapeutic purposes.

As a student of chemistry, one can appreciate the impact that such structures can have in the field of drug discovery. This compound, although it may seem complex at first glance, embodies the fascinating interplay between structure and function that defines medicinal chemistry. Researchers are intrigued by how small modifications can lead to significant changes in activity, opening doors to tailored therapies.

In conclusion, 2-(2-chloroethyl)-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride represents not just a single chemical entity, but a promising avenue for exploring new frontiers in both synthetic and medicinal chemistry.

Synonyms
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-2-(2-CHLOROETHYL)-, HYDROCHLORIDE
RefChem:1087711
27160-30-1
NSC 50599
2-(2-Chloroethyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
Isoquinoline, 2-(2-chloroethyl)-1,2,3,4-tetrahydro-, hydrochloride