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Clobazam

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Identification
Molecular formula
C16H13Cl2N2O2
CAS number
22316-47-8
IUPAC name
[2-(2-chloroethyl)-4-oxo-2,3-dihydro-1,3-benzoxazin-6-yl]ammonium;chloride
State
State

At room temperature, Clobazam is a solid. It is usually provided in tablet form for administration.

Melting point (Celsius)
227.00
Melting point (Kelvin)
500.15
Boiling point (Celsius)
299.50
Boiling point (Kelvin)
572.65
General information
Molecular weight
300.74g/mol
Molar mass
300.7430g/mol
Density
1.3100g/cm3
Appearence

Clobazam appears as a white to off-white crystalline powder. It generally exhibits a slightly bitter taste and has no distinct odor.

Comment on solubility

Solubility of [2-(2-chloroethyl)-4-oxo-2,3-dihydro-1,3-benzoxazin-6-yl]ammonium;chloride

The compound [2-(2-chloroethyl)-4-oxo-2,3-dihydro-1,3-benzoxazin-6-yl]ammonium;chloride exhibits notable solubility characteristics that are influenced by its structure and functional groups. Some key points regarding its solubility are as follows:

  • Polar Nature: The presence of the ammonium ion and chloride counter ion contribute to its overall polar characteristics, promoting significant solubility in polar solvents.
  • Solvent Compatibility: This compound tends to be more soluble in water and alcohols, making it suitable for use in aqueous solutions.
  • Influence of Functional Groups: The chloroethyl and benzoxazin moieties provide opportunities for favorable interactions with solvent molecules, impacting solubility.
  • pH Dependency: Solubility can also be affected by the pH of the solution, particularly given the basic nature of the ammonium group.

However, while the compound demonstrates good solubility in relevant solvents, conditions such as temperature and ionic strength can further modulate its solubility profile. This allows for versatility in applications where solubility is crucial for efficacy.

Interesting facts

Interesting Facts About [2-(2-chloroethyl)-4-oxo-2,3-dihydro-1,3-benzoxazin-6-yl]ammonium;chloride

[2-(2-chloroethyl)-4-oxo-2,3-dihydro-1,3-benzoxazin-6-yl]ammonium;chloride is a fascinating compound that bridges the worlds of organic chemistry and medicinal applications. Here's why this compound is noteworthy:

  • Biological Significance: Compounds like this one are often explored for their potential biological activity. The presence of the benzoxazine structure suggests possible uses in pharmaceuticals, owing to its role in various biological pathways.
  • Chloroethyl Moiety: The incorporation of a chloroethyl functional group can confer unique reactivity, making this compound potentially useful in synthetic applications. Chloroethyl groups are often exploited in the preparation of other chemical entities.
  • Research Potential: This compound may serve as an important lead compound in drug discovery, where researchers evaluate its efficacy against target pathogens or cancer cells.
  • Ammonium Ion: The ammonium component enhances solubility and can influence the bioavailability of the compound, which is a critical consideration in pharmaceutical development.
  • Synthetic Routes: Understanding the synthesis of such compounds offers insights into the methodologies used in organic synthesis, such as nucleophilic substitutions and cyclization reactions.

Furthermore, as a compound belonging to a class of materials with potential for medicinal chemistry, it raises intriguing questions concerning its mechanism of action. As one researcher famously stated, "The study of chemical compounds is as much a journey into the unknown as it is a quest for knowledge."

As you delve deeper into the world of organic compounds, remember that each structure tells a story and opens the door to numerous possibilities in scientific exploration!

Synonyms
Aminochlorthenoxazin hydrochloride
3443-15-0
E0571LF5SO
UNII-E0571LF5SO
A 350
2-(beta-Chloroethyl)-2,3-dihydro-4-oxo-6-amino-1,3-benzoxazine hydrochloride
6-Amino-2-(2-chloroethyl)-2,3-dihydro-4H-1,3-benzoxazin-4-one hydrochloride
4H-1,3-BENZOXAZIN-4-ONE, 2,3-DIHYDRO-6-AMINO-2-(2-CHLOROETHYL)-, HYDROCHLORIDE
Q27276686