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Thiotepa

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Identification
Molecular formula
C6H12Cl2N2OPS
CAS number
52-24-4
IUPAC name
2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide
State
State

At room temperature, Thiotepa is in a solid state.

Melting point (Celsius)
52.00
Melting point (Kelvin)
325.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
189.71g/mol
Molar mass
189.7120g/mol
Density
1.0579g/cm3
Appearence

Thiotepa appears as a white crystalline powder. It is not colored and its crystal structure makes it granular.

Comment on solubility

Solubility of 2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide

The solubility of the compound 2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide, which is often referred to in shorthand as Chlorosulfanyl compound, is influenced by multiple factors due to its complex structure.

Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while non-polar groups may repel interaction with water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly improve solubility in water, making it more soluble in aqueous solutions.
  • Molecular Structure: The length of carbon chains and steric hindrance can also affect how easily the molecule interacts with solvents.

In general, one can expect that the solubility characteristics of this compound might fall into the following categories:

  1. Moderate solubility in polar solvents like water, due to its polar groups.
  2. Increased solubility in organic solvents, particularly those that can interact favorable with sulfur and chlorine functionalities.
  3. Poor solubility in non-polar solvents, as the compound's structure likely contains regions that do not interact well with such mediums.

To summarize, the solubility of this compound can be described as variable, contingent on the solvent employed and the specific conditions such as temperature and concentration. As with many organic compounds, predicting solubility requires a thorough understanding of both chemical structure and solvent properties.

Interesting facts

Interesting Facts about 2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide

The compound 2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide is a fascinating molecule that showcases the intricacies of chemical synthesis and therapeutic applications. Here are some captivating aspects of this compound:

  • Pharmaceutical Potential: This compound is linked to the development of medicinal agents, particularly in the realm of cancer treatment. Its unique structure may influence how it interacts with biological targets.
  • Chlorine's Role: The presence of chlorine atoms suggests that the compound could have distinctive properties, as halogens are known to modify the physical and chemical characteristics of a molecule.
  • Sulfanyl Group: The sulfanyl (thioether) groups within the compound are notable for enhancing the compound's reactivity and potentially contributing to its biological profile.
  • Complex Structure: The multi-functional nature of this molecule, with amide, acetyl, and chlorinated components, emphasizes the complexity and versatility often desired in drug design.

In the words of famed chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” Embracing this approach in the study of such compounds can lead to significant breakthroughs in medicinal chemistry. The ongoing research into compounds like this one continues to pave the way for innovative therapies and deeper understandings of biochemical processes.

As scientists examine the interactions and reactivity of 2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide, they provide critical insights that can potentially influence the future development of targeted drug therapies. This compound stands as a testament to the fascinating world of organic chemistry and the endless possibilities it harbors for human health.

Synonyms
S-176 Mustard
UNII-5UM10NZN3Y
5UM10NZN3Y
NSC 41126
S 176 mustard
N,N'-Ethylene-bis(2-chloroethylthio)acetamide
NSC-41126
DTXSID60236045
N,N'-Ethylenebis((2-chloroethylthio)acetamide)
N,N'-bis(2-chloroethylthioacetyl)-1,2-ethylenediamine
DTXCID60158536
870-05-3
Acetamide, N,N'-1,2-ethanediylbis(2-((2-chloroethyl)thio)-
ACETAMIDE, N,N'-ETHYLENEBIS(2-((2-CHLOROETHYL)THIO)-
S 46 (VAN)
2-(2-chloroethylsulfanyl)-N-[2-[[2-(2-chloroethylsulfanyl)acetyl]amino]ethyl]acetamide
WLN: G2S1VM2MV1S2G
NSC41126
N,N'-Ethylenebis[(2-chloroethyl)thio]acetamide
Acetamide,N'-ethylenebis[2-[(2-chloroethyl)thio]-
Q27262894
Acetamide,N'-1,2-ethanediylbis[2-[(2-chloroethyl)thio]-