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Lomustine

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Identification
Molecular formula
C9H16ClN3O2
CAS number
13010-47-4
IUPAC name
2-(2-chlorophenyl)-1-(diaminomethylene)guanidine
State
State
Solid under standard conditions of temperature and pressure.

It is stable under ordinary conditions of use and storage.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
233.68g/mol
Molar mass
233.6840g/mol
Density
0.1953g/cm3
Appearence
The compound is generally a white to off-white crystalline solid.

The appearance might slightly vary depending on the presence of impurities.

Comment on solubility

Solubility of 2-(2-chlorophenyl)-1-(diaminomethylene)guanidine

The solubility of 2-(2-chlorophenyl)-1-(diaminomethylene)guanidine is influenced by several factors, which are important to consider when working with this compound:

  • Polarity: This compound has polar functional groups, which can enhance its solubility in polar solvents, such as water and alcohols.
  • Hydrophilicity: The presence of amino groups contributes to its hydrophilic nature, potentially allowing for stronger interactions with water molecules.
  • Temperature Effects: Temperature can significantly influence solubility; generally, solubility increases with temperature for many solid compounds.
  • pH Sensitivity: Changes in pH can also impact solubility due to protonation or deprotonation of the functional groups, affecting the overall behavior of the compound in solution.

In practical applications, it's essential to note that while the compound exhibits some solubility in aqueous environments, the extent can vary based on the specific conditions mentioned above. Therefore, conducting empirical solubility tests under relevant conditions is advisable to obtain accurate and reliable solubility data for 2-(2-chlorophenyl)-1-(diaminomethylene)guanidine.

Interesting facts

Interesting Facts About 2-(2-chlorophenyl)-1-(diaminomethylene)guanidine

2-(2-chlorophenyl)-1-(diaminomethylene)guanidine is a fascinating compound in the realm of chemistry, notable for its unique structure and diverse applications. This compound can be categorized under guanidine derivatives, which have captured the attention of researchers for various reasons.

Key Characteristics

  • Pharmaceutical Potential: Compounds like this one are often investigated for their pharmaceutical applications, such as serving as effective intermediates in the synthesis of various drugs.
  • Biological Activity: The presence of the chlorophenyl group in its structure may contribute to potential biological activities, making it a candidate for studies in medicinal chemistry.
  • Versatile Reactions: Guanidine derivatives are known for their ability to undergo numerous chemical reactions, offering versatility in synthetic pathways.

Noteworthy Quotes from Researchers

As the chemist Robert H. Grubbs famously stated, “The best reaction is the one that gives you the product you want.” In studying compounds like 2-(2-chlorophenyl)-1-(diaminomethylene)guanidine, chemists seek to optimize reactions to yield valuable pharmaceuticals.

Future Directions

Researchers are continually exploring the utility of guanidine derivatives in:

  • Agricultural Applications: As potential agrochemicals or biopesticides.
  • Material Science: By examining their properties as catalysts or polymers.

As such, 2-(2-chlorophenyl)-1-(diaminomethylene)guanidine serves as a reminder of the intricate connections between molecular structure and application, highlighting the potential waiting to be uncovered in the world of chemistry.

Synonyms
137588-53-5
1-(2-chlorophenyl)biguanide
N-(2-chlorophenyl)-N'-(diaminomethylene)guanidine
49872-43-7
2-(2-chlorophenyl)-1-(diaminomethylidene)guanidine
2-Chloro-Phenyl biguanide
N-(2-chlorophenyl)imidodicarbonimidic diamide
Imidodicarbonimidic diamide, N-(2-chlorophenyl)-
CHEMBL42752
MFCD04225715
N-(2-CHLOROPHENYL)-1-[(DIAMINOMETHYLIDENE)AMINO]METHANIMIDAMIDE
Maybridge1_006916
GQ6L3T7RNE
SCHEMBL725722
SCHEMBL29518838
DTXSID00274880
ALBB-025591
BDBM50053629
SBB072601
STK107576
AKOS002224830
AKOS003334648
NCGC00340582-01
LS-08646
PD129495
H35217
AB01331795-02
N-(2-chlorophenyl)dicarbonimido/ic diamide/imido
2-(2-chlorophenyl)-1-(diaminomethylene)guanidine
AG-205/04772048
guanidine, N-(2-chlorophenyl)-N'-(diaminomethylene)-
(3,3-diamino-1-imino-2-azaprop-2-enyl)(2-chlorophenyl)amine
1-{[{[AMINO(IMINO)METHYL]AMINO}(IMINO)METHYL]AMINO}-2-CHLOROBENZENE