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Chlorphenoxamine hydrochloride

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Identification
Molecular formula
C8H6Cl2N2O
CAS number
2863-98-5
IUPAC name
[2-(2-chlorophenyl)-2H-1,3,4-oxadiazol-5-ylidene]ammonium;chloride
State
State
The compound is typically in a solid state at room temperature, appearing as a crystalline powder.
Melting point (Celsius)
186.00
Melting point (Kelvin)
459.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
292.20g/mol
Molar mass
292.1990g/mol
Density
1.3000g/cm3
Appearence

The compound appears as a white or off-white crystalline powder. It is typically odorless or has a faint characteristic smell.

Comment on solubility

Solubility of [2-(2-chlorophenyl)-2H-1,3,4-oxadiazol-5-ylidene]ammonium;chloride

The solubility of the compound [2-(2-chlorophenyl)-2H-1,3,4-oxadiazol-5-ylidene]ammonium;chloride can be influenced by several factors, including temperature, solvent polarity, and molecular interactions. Here are key points to consider:

  • Solubility in Water: This compound is expected to have reasonable solubility in polar solvents such as water due to the presence of the ammonium group, which generally increases solvation through hydrogen bonding.
  • Solubility in Organic Solvents: The anionic component, chloride, may complicate solubility in non-polar solvents. Hence, it is likely poorly soluble in organic solvents like hexane or toluene.
  • Temperature Effects: As temperature increases, the solubility of ionic compounds like ammonium salts usually increases, potentially making this compound more soluble at elevated temperatures.
  • pH Influence: The **ionic nature** of the ammonium part can also make the solubility sensitive to the pH of the solution; altering the pH can lead to changes in the compound's solubility.

In summary, while the presence of the ammonium group suggests a certain degree of solubility in water, the actual **solubility behavior** will heavily depend on the specific **solvent** and **environmental conditions**. As such, experimentation will provide the best insight into its solubility profile.

Interesting facts

Interesting Facts about 2-(2-chlorophenyl)-2H-1,3,4-oxadiazol-5-ylidene]ammonium;chloride

This intriguing compound, known for its unique structure, belongs to the class of oxadiazole derivatives, which have garnered significant attention in the world of organic chemistry. Here are some captivating insights that showcase its relevance:

  • Pharmacological Potential: Compounds containing oxadiazole rings often exhibit a range of biological activities. This specific compound has been studied for its potential as an anti-inflammatory and anticancer agent.
  • Versatile Applications: Beyond its medicinal applications, oxadiazole derivatives are utilized in the development of materials, including organic light-emitting diodes (OLEDs) and as precursors in organic synthesis.
  • Substituent Effects: The presence of the chlorophenyl group can significantly influence the compound's electronic properties and reactivity. This feature makes it an interesting subject for studies focused on structure-activity relationships (SAR).
  • Research Interest: The synthesis of novel ammonium salts like this one opens new avenues in the development of Lewis acid catalysts, which are pivotal in various organic reactions.
  • Environmental Impact: As scientists increasingly focus on green chemistry, studying such compounds can lead to the development of less toxic derivatives, reducing environmental hazards associated with traditional reagents.

In conclusion, the remarkable attributes of 2-(2-chlorophenyl)-2H-1,3,4-oxadiazol-5-ylidene]ammonium;chloride make it a compound of growing interest in both academic research and practical applications. As chemists continue to unveil its secrets, the potential for advancements in pharmaceuticals and material science seems boundless.

Synonyms
delta(sup 2)-1,3,4-Oxadiazoline, 2-(o-chlorophenyl)-5-imino-, hydrochloride, hydrate
5711-56-8
2-(o-Chlorophenyl)-5-imino-delta(sup 2)-1,3,4-oxadiazoline hydrochloride hydrate