Chlorphenamine | Solubility of Things

Identification

Molecular formula

C₁₆H₁₉ClNO

CAS number

132-22-9

IUPAC name

2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine

State

Chlorphenamine at room temperature is generally found in a solid state. It is typically distributed in a salt form when used in medications, providing it with certain solubility properties to ensure effective delivery within the body. In its pure form, it manifests as a crystalline solid.

Melting point (Celsius)

93.00

Melting point (Kelvin)

366.15

Boiling point (Celsius)

385.00

Boiling point (Kelvin)

658.15

General information

Molecular weight

270.78g/mol

Molar mass

270.7830g/mol

Density

1.1450g/cm³

Appearence

Chlorphenamine is typically a white to off-white crystalline powder. It is known for its slight odor and is practically odorless in its pure form. The compound is typically used in its maleate salt form within pharmaceutical preparations, which may appear differently in color and texture based on the formulation.

Comment on solubility

Solubility of 2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine

The solubility of 2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine can be influenced by a number of factors. Generally, compounds containing aromatic groups, such as this one, exhibit varied solubility in different solvents based on their structural characteristics.

Key Points on Solubility:

Polarity: The presence of methoxy and chlorine groups can affect the overall polarity of the compound, potentially enhancing solubility in polar solvents.
Solvent Compatibility: Aromatic compounds often show good solubility in non-polar solvents; therefore, organic solvents such as ethanol or dichloromethane could be suitable.
Hydrogen Bonding: The ability of the molecule to participate in hydrogen bonding (due to the methoxy group) may enhance solubility in polar protic solvents.
Temperature Effects: Solubility can increase with temperature, which should be taken into account during solubility studies.

In general, when assessing the solubility of 2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine, it is crucial to consider both intermolecular interactions and the solvent environment to predict behavior accurately.

Interesting facts

Interesting Facts about 2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine

2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine is a fascinating compound that has captured the interest of researchers and chemists alike. Here are some intriguing points to note:

Pharmaceutical Relevance: This compound belongs to a class of chemicals that can be investigated for therapeutic applications. Its structure suggests potential activity in various biological systems.
Chlorine Substituent: The presence of the chlorine atom enhances the compound's potential for interactions in chemical reactions, as chlorine is known to influence the electron distribution within the molecule.
Dimethylamino Group: The N,N-dimethyl group contributes to the basicity and solubility characteristics of the compound, which may be significant for its activity in biological contexts.
Versatile Structure: The combination of the methoxy group and the phenyl rings provides a versatile scaffold that chemists can utilize to modify the compound for various experimental purposes, making it a valuable compound for synthesis.
Research Potential: Given its unique structure, this compound could be a candidate for research into novel pharmacological agents, especially in the fields of medicinal and organic chemistry.

As a compound with a complex arrangement of functional groups, 2-[(2-chlorophenyl)-phenyl-methoxy]-N,N-dimethyl-ethanamine is a prime example of how subtle variations in chemical structure can lead to significant changes in biological activity and chemical reactivity. As the saying goes, "The devil is in the details!"

Understanding compounds like this not only broadens our knowledge but also enhances our ability to innovate in various scientific disciplines.