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Bupropion Hydrochloride

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Identification
Molecular formula
C13H19ClNO3
CAS number
31677-93-7
IUPAC name
[2-[(2-chlorophenyl)carbamoyloxy]cyclohexyl]-diethyl-ammonium;chloride
State
State

At room temperature, Bupropion Hydrochloride is in a solid state. It is stable under normal conditions, but should be kept in a tightly closed container away from moisture.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.00
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.00
General information
Molecular weight
276.77g/mol
Molar mass
276.2040g/mol
Density
1.2000g/cm3
Appearence

Bupropion Hydrochloride is typically found as a white to slightly off-white crystalline powder. It may exist in different polymorphic forms, which can result in variations in its appearance.

Comment on solubility

Solubility of 2-[(2-chlorophenyl)carbamoyloxy]cyclohexyl-diethyl-ammonium;chloride

The solubility of the compound 2-[(2-chlorophenyl)carbamoyloxy]cyclohexyl-diethyl-ammonium;chloride is influenced by various factors, including its ionic nature and the presence of hydrophilic and hydrophobic groups. Here are some key points regarding its solubility:

  • Ionic Character: As a quaternary ammonium salt, this compound enhances solubility in polar solvents such as water, due to the positive charge on the ammonium ion.
  • Hydrophobic Interactions: The 2-chlorophenyl and cyclohexyl groups introduce hydrophobic characteristics, which can affect overall solubility in non-polar solvents.
  • Temperature Dependency: Like many salts, solubility can increase with temperature, allowing for greater dissolution in warm solvents.
  • pH Influence: The solubility may also vary with the pH of the solution, as changes can impact the ionization state of the molecule.

In practical applications, this compound is typically expected to be more soluble in environments where polar solvents are present. Thus, it is essential to consider the solvent environment when evaluating the suitability and behavior of this compound in various chemical processes.

Interesting facts

Interesting Facts about 2-[(2-chlorophenyl)carbamoyloxy]cyclohexyl-Diethyl-Ammonium Chloride

This compound, known for its unique structure and intriguing properties, belongs to the class of ammonium salts. Here are some fascinating insights:

  • Biological Significance: Compounds with similar structures are often investigated for their potential pharmaceutical applications, including anti-inflammatory and analgesic effects. Understanding such compounds can pave the way for new drug development.
  • Structure-Activity Relationship: The presence of a chlorophenyl group plays a crucial role in modulating biological activity. Scientists explore how slight modifications in the molecule can enhance efficacy and reduce side effects.
  • Versatile Synthesis: The synthesis of this compound involves multiple steps, combining cyclohexyl derivatives with chlorinated phenyl groups. Such methodologies provide valuable insights into organic chemistry and the importance of functional group manipulation.
  • Ionization and Solubility: As an ammonium salt, it features an ionic character, impacting its solubility in various solvents. This solubility can influence both its bioavailability and how it interacts within biological systems.
  • Pharmaceutical Formulations: The compound may also be explored as a part of formulations that require controlled release or targeted delivery of therapeutic agents, showcasing its potential in drug design.

Overall, the study of 2-[(2-chlorophenyl)carbamoyloxy]cyclohexyl-diethyl-ammonium chloride not only deepens our understanding of chemical compounds but also highlights the intricate relationship between chemical structure and biological activity. As research continues, we may uncover further applications that could greatly benefit various fields, particularly pharmaceuticals.

Synonyms
o-Chlorocarbanilic acid 2-(diethylamino)cyclohexyl ester hydrochloride
17114-34-0
K 1101
CARBANILIC ACID, o-CHLORO-, 2-(DIETHYLAMINO)CYCLOHEXYL ESTER, HYDROCHLORIDE