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Bupropion Hydrochloride

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Identification
Molecular formula
C13H21Cl2NO
CAS number
31677-93-7
IUPAC name
2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride
State
State

At room temperature, Bupropion Hydrochloride is found in a solid state. It remains a powder under standard conditions and should be stored in a dry, cool environment to maintain its stability and efficacy.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.00
Boiling point (Celsius)
455.30
Boiling point (Kelvin)
728.40
General information
Molecular weight
276.20g/mol
Molar mass
276.2040g/mol
Density
1.1250g/cm3
Appearence

Bupropion Hydrochloride appears as a white, crystalline powder that is highly soluble in water. It lacks significant odor and is commonly used in tablet form for medicinal purposes. The powder exhibits a standard crystalline structure and should be free from color or foreign particulates.

Comment on solubility

Solubility of 2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride

The solubility of 2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride is a noteworthy characteristic of this compound that affects its application in various fields. This ammonium salt is generally considered to be soluble in water due to its ionic nature, which facilitates interaction with polar solvents. The presence of the diethylammonium moiety enhances solubility because:

  • Hydrophilicity: The ammonium functional group can form hydrogen bonds with water molecules, aiding its dissolution.
  • Charge: The ionic charge allows it to dissociate in solution, which increases solubility.
  • Chain Length: The diethyl groups provide a balance, maintaining solubility while also furnishing hydrophobic characteristics.

Moreover, the introduction of the 2-chlorophenyl group could influence the solubility profile. While chlorinated aromatic compounds can exhibit increased hydrophobicity, the overall influence on solubility depends on the balance between the hydrophilic and hydrophobic parts of the molecule. Thus, the solubility can be described by the interplay of the following factors:

  • Temperature: Solubility often increases with temperature.
  • Concentration: Higher concentrations of the compound can lead to decreased solubility due to saturation.
  • Presence of other solutes: Non-polar substances can decrease solubility through competition for solvation.

In conclusion, 2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium;chloride is expected to display considerable solubility in aqueous environments, making it a versatile compound in chemical and pharmaceutical applications.

Interesting facts

Exploring 2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium chloride

2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium chloride is a fascinating compound that demonstrates the intricate relationships between organic chemistry and pharmacology. Here are some intriguing facts about this compound:

  • Ammonium Ion: This compound features a quaternary ammonium structure, where the central nitrogen atom is bonded to four carbon groups. This structure is significant for its behavior as an ionic compound, greatly influencing its solubility in water.
  • Biological Relevance: It has potential applications in medicinal chemistry, where compounds with quaternary ammonium groups are often found in antimicrobial agents and as muscle relaxants. The ability to selectively target specific cellular pathways makes it a subject of interest for drug design.
  • Chlorine Substituent: The presence of the chloro group indicates that this compound can participate in various chemical reactions typical for haloalkanes, which may enhance its reactivity and biological activity.
  • Structure Activity Relationship (SAR): Investigating the structure-activity relationship of this compound could yield insights into how slight modifications can affect its efficacy and safety, which is a crucial aspect of pharmaceutical development.
  • Interactions: It has implications in understanding drug interactions, particularly through its binding capabilities within biological systems. This opens up avenues to explore how it affects cellular communication and signaling.

As researchers continue to unveil the complexities of compounds like 2-[(2-chlorophenyl)carbamoyloxy]ethyl-diethyl-ammonium chloride, we gain a deeper appreciation for the intricate dance between molecules within biological systems. This compound exemplifies the rich challenges and opportunities in organic synthesis and pharmacology.

Synonyms
2-(Diethylamino)ethyl o-chlorocarbanilate hydrochloride
20229-00-9
NSC 40068
K 491
o-Chlorocarbanilic acid 2-(diethylamino)ethyl ester hydrochloride
CARBANILIC ACID, o-CHLORO-, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE