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Chlorphenamide

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Identification
Molecular formula
C8H10ClNS2
CAS number
63993-05-7
IUPAC name
2-[(2-chlorophenyl)disulfanyl]ethanamine
State
State

At room temperature, chlorphenamide exists in a solid state. It is generally stable under normal temperatures and pressures.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
235.75g/mol
Molar mass
235.7400g/mol
Density
1.4079g/cm3
Appearence

Chlorphenamide appears as a crystalline solid with a pale yellow color. It is usually found in powdered form for laboratory and research purposes.

Comment on solubility

Solubility of 2-[(2-chlorophenyl)disulfanyl]ethanamine

2-[(2-chlorophenyl)disulfanyl]ethanamine, with its complex structure, presents intriguing solubility characteristics influenced by both its functional groups and aromatic components. Understanding the solubility of this compound requires considering several factors:

  • Polarity: The presence of the amine group contributes to the polarity of the molecule, which generally enhances solubility in polar solvents like water.
  • Aromaticity: The chlorophenyl part of the molecule introduces hydrophobic characteristics, which may limit solubility in water but increase compatibility with organic solvents.
  • Disulfide Link: The disulfanyl moiety can lead to specific interactions with other molecules, potentially allowing for more favorable solubility conditions in certain environments.

In practice, aqueous solubility may be limited due to the opposing effects of polarity and hydrophobicity. It is common for compounds with similar structures to exhibit:

  • Higher solubility in: Organic solvents (like ethanol and acetone).
  • Lower solubility in: Polar solvents such as water, potentially forming insoluble aggregates.

Overall, the solubility profile of 2-[(2-chlorophenyl)disulfanyl]ethanamine showcases the intricate balance between hydrophilic and hydrophobic interactions, making it an interesting subject for further study in various solvent systems.

Interesting facts

Exploring 2-[(2-chlorophenyl)disulfanyl]ethanamine

2-[(2-chlorophenyl)disulfanyl]ethanamine, a compound with intriguing structural characteristics, raises interest in both medicinal chemistry and synthetic applications. Here are some notable facts to consider:

  • Structural Significance: The presence of the disulfanyl (–S–S–) moiety in its structure plays a crucial role in the compound's reactivity and stability, influencing how it interacts with various biological targets.
  • Chlorophenyl Group: The chlorine atom on the phenyl ring can enhance the compound's electrophilicity, making it a potential candidate for further medicinal modifications aimed at enhancing therapeutic efficacy.
  • Potential Applications: Research suggests that compounds featuring disulfide bonds may exhibit antioxidant properties, which are valuable in developing treatments for oxidative stress-related diseases.
  • Biological Interest: With growing interest in compounds that target specific cellular pathways, the unique attributes of 2-[(2-chlorophenyl)disulfanyl]ethanamine may lend to investigations in cancer and other conditions where protein folding and stability are compromised.
  • Synthetic Pathways: This compound can be synthesized through various methods, including nucleophilic substitution reactions followed by disulfide bond formation, highlighting the versatility of sulfur chemistry in creating complex organic molecules.

Overall, the investigation into 2-[(2-chlorophenyl)disulfanyl]ethanamine not only showcases the complexities of synthetic organic chemistry but also hints at its potential utility in the realm of pharmaceuticals.