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Cimetidine

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Identification
Molecular formula
C10H16N6
CAS number
51481-61-9
IUPAC name
2-[2-(cyclohexylamino)ethyl]guanidine
State
State

Cimetidine is typically in a solid state at room temperature, commonly found as a crystalline powder in pharmaceutical applications.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.15
Boiling point (Celsius)
425.00
Boiling point (Kelvin)
698.15
General information
Molecular weight
252.37g/mol
Molar mass
252.3670g/mol
Density
1.1400g/cm3
Appearence

Cimetidine generally appears as a white to pale yellow crystalline powder. It is odorless, and its crystals are often finely divided to allow for usage in various pharmaceutical formulations.

Comment on solubility

Solubility of 2-[2-(cyclohexylamino)ethyl]guanidine

The solubility of 2-[2-(cyclohexylamino)ethyl]guanidine is an important factor for its application in various chemical and biological contexts. This compound exhibits unique solubility characteristics due to its molecular structure.

  • Polarity: The presence of both amine and guanidine functional groups contributes to a significant polar character, which typically enhances water solubility.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature. Thus, higher temperatures could lead to a greater dissolution rate.
  • Solvent Compatibility: This compound may have varied solubility in organic solvents, influenced by chain length and branching of the solvent molecules.

According to solubility principles, the phenomena of "like dissolves like" suggest that 2-[2-(cyclohexylamino)ethyl]guanidine will be more soluble in polar solvents than in nonpolar ones. Nonetheless, empirical testing remains essential to establish its precise solubility parameters under specified conditions.

Overall, understanding its solubility is crucial for effective utilization in applications such as drug formulation, where the ability to dissolve in biological fluids can greatly impact efficacy.

Interesting facts

Exploring 2-[2-(cyclohexylamino)ethyl]guanidine

2-[2-(cyclohexylamino)ethyl]guanidine is a fascinating chemical compound that plays a significant role in both biological and medicinal chemistry. Below are some engaging facts about this compound:

  • Pharmacological Relevance: This compound is known for its potency as a guanidine derivative, which can influence several biological pathways. Guanidines are often studied for their role in antihypertensive medications and other therapeutic uses.
  • Mechanism of Action: The compound acts by modulating various receptor systems in the body, showcasing its potential as a biologically active compound. It has been explored in research for its ability to enhance synaptic transmission.
  • Cyclohexylamino Group: The presence of the cyclohexylamino group brings unique steric and electronic properties to the compound, making it an interesting subject for structure-activity relationship studies.
  • Potential Applications: Research has indicated that guanidine derivatives, including this one, may have applications ranging from neurological therapies to muscle relaxants in medical settings.
  • Synthesis Insights: The synthesis of 2-[2-(cyclohexylamino)ethyl]guanidine can be accomplished through various organic reactions, providing chemists with valuable techniques for creating similar compounds in the lab.

In conclusion, 2-[2-(cyclohexylamino)ethyl]guanidine is more than just a compound; it is a gateway into the world of pharmaceutical chemistry, showcasing the intricate relationship between molecular structure and biological function. As research continues, the full potential of this compound remains to be explored!