Skip to main content

Cimetidine

ADVERTISEMENT
Identification
Molecular formula
C10H16N6
CAS number
51481-61-9
IUPAC name
2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine
State
State

Cimetidine is typically a solid at room temperature.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.15
Boiling point (Celsius)
311.00
Boiling point (Kelvin)
584.15
General information
Molecular weight
252.36g/mol
Molar mass
252.3560g/mol
Density
1.9000g/cm3
Appearence

Cimetidine is a white to pale yellow, crystalline solid that has no significant odor. It is typically found in the form of tablets or an injectable solution for medical use.

Comment on solubility

Solubility of 2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine

The solubility of 2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine is an intriguing aspect that can influence its applications and behavior in various environments.

When discussing solubility, several key factors come into play:

  • Solvent Polarity: This compound is likely to show varying solubility in polar and nonpolar solvents due to the presence of both hydrophilic (guanidine) and hydrophobic (cyclohexyl) components.
  • Temperature Effects: Increased temperature generally enhances solubility, but the specific behavior of this guanidine derivative can differ, and experimental data is essential for precise determination.
  • pH Influence: Given that guanidines can act as bases, the pH of the surrounding solution can significantly impact solubility. In acidic environments, solubility might increase due to protonation, making it more soluble in water.

In summary, while the solubility of 2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine is influenced by multiple factors, experimental verification is crucial to gain a comprehensive understanding. It is worth noting that the compound's unique structural features result in a complex interplay between its solubility in various media.

Interesting facts

Interesting Facts About 2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine

2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine is a fascinating compound that showcases the intricate world of organic chemistry. This compound is particularly noteworthy for several reasons:

  • Pharmacological Importance: It has been studied for its potential applications in medicinal chemistry, particularly as an antidepressant and anxiolytic agent. Its unique structure allows for interactions that may alleviate symptoms of anxiety and depression.
  • Structure-Activity Relationship: The presence of the cyclohexyl group contributes to its pharmacological properties. This structure can enhance lipophilicity, potentially influencing how the compound interacts with biological targets.
  • Diverse Applications: Beyond its medicinal potential, this compound may also find roles in other fields such as materials science, where its guanidine moiety could be utilized in synthesizing polymers or coatings.
  • Hybrid Nature: The combination of both cycloalkane and amine functionalities makes this compound a hybrid that demonstrates versatility in chemical reactivity and interaction with various substrates.

Overall, 2-[2-[cyclohexyl(methyl)amino]ethyl]guanidine exemplifies how seemingly simple modifications in chemical structure can lead to diverse and significant biological activities. As chemistry enthusiasts delve into the world of such compounds, they uncover pathways that may lead to revolutionary breakthroughs in therapeutic measures and materials development.

Synonyms
NIOSH/MF3690200
AZ 122
MF36902000
1-(2-(N-Methylcyclohexylamino)ethyl)guanidine
Guanidine, 1-(2-(N-methylcyclohexylamino)ethyl)-