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Lobeline

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Identification
Molecular formula
C15H25NO2
CAS number
90-69-7
IUPAC name
2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol
State
State

At room temperature, lobeline is typically found in a solid state.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
123.00
Boiling point (Kelvin)
396.15
General information
Molecular weight
275.38g/mol
Molar mass
275.3960g/mol
Density
1.0290g/cm3
Appearence

Lobeline is a white or off-white crystalline solid. It often occurs as a powder and may have a slight characteristic odor.

Comment on solubility

Solubility of 2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol

The solubility of 2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol is influenced by a variety of factors, primarily due to its molecular structure and functional groups. This compound features both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, leading to unique solubility characteristics:

  • Hydrophilic Component: The presence of the diethylamino group enhances solubility in polar solvents, making it more soluble in water and alcohols.
  • Hydrophobic Component: The phenyl group contributes to hydrophobic interactions, which can hinder solubility in highly polar environments.
  • Temperature Dependence: As with many organic compounds, solubility tends to increase with temperature, potentially allowing for greater dissolution in various solvents at elevated temperatures.

Overall, the balance between these hydrophilic and hydrophobic features creates a compound that is moderately soluble in polar solvents but may show reduced solubility in nonpolar solvents. Thus, understanding the nature of the solvent is essential for predicting the solubility of 2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol:

  • Polar solvents: Good solubility expected.
  • Nonpolar solvents: Limited solubility anticipated.

In summary, evaluating the solubility of this compound requires careful consideration of its structural components and environmental conditions, providing valuable insights for applications in medicinal chemistry and drug formulation.

Interesting facts

Interesting Facts About 2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol

2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol, often abbreviated as DEAE-PE, is a fascinating compound in the realm of organic chemistry. Here are some noteworthy points to consider:

  • Structure and Functionality: This compound features a unique molecular structure that includes both an ether and an alcohol functional group, making it a versatile compound in synthetic applications.
  • Biological Relevance: Due to its diethylamino moiety, DEAE-PE can significantly interact with biological systems. Compounds with similar structures are often studied for their potential pharmacological effects and applications.
  • Solubility Properties: The presence of both hydrophilic (alcohol) and hydrophobic (phenyl) components allows DEAE-PE to exhibit interesting solubility properties, which can be critical in various chemical reactions.
  • Applications in Research: Scientists explore DEAE-PE in the context of drug design and development, especially for targeting specific cellular pathways and enhancing drug delivery mechanisms.
  • Sustainability in Chemistry: Researchers are increasingly looking at compounds like DEAE-PE for their potential role in green chemistry initiatives, particularly in minimizing waste and reducing the use of hazardous solvents.

As we delve deeper into the chemistry of compounds like 2-[2-(diethylamino)ethoxy]-1-phenyl-ethanol, it becomes clear that they hold the key to numerous innovations, bridging the gap between fundamental science and practical application. As one scientist aptly noted, "The true beauty of chemistry lies in unraveling the mysteries of structure and reactivity."


Synonyms
27078-43-9
alpha-((2-(Diethylamino)ethoxy)methyl)benzyl alcohol
BRN 2456511
BENZYL ALCOHOL, alpha-((2-(DIETHYLAMINO)ETHOXY)METHYL)-
3-06-00-04577 (Beilstein Handbook Reference)
RefChem:328564
NO-30
2-[2-(diethylamino)ethoxy]-1-phenylethanol
2-(2-(Diethylamino)ethoxy)-1-phenylethanol
SCHEMBL9326907
DTXSID30949837
MFCD00093875
SY282946
WS-00373
D86783
2-[2-(Diethylamino)ethoxy]-1-phenylethan-1-ol