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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenyl-butanoate
State
State

At room temperature, lidocaine is in a crystalline solid state. It is commonly processed into forms suitable for injection or topical application, such as creams and ointments, which are used medically for their local anesthetic properties.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
235.34g/mol
Molar mass
235.3390g/mol
Density
0.9220g/cm3
Appearence

Lidocaine typically appears as a white, crystalline powder. It is odorless and has a slightly bitter taste. Lidocaine is commonly used in its hydrochloride salt form, which is more soluble in water, making it suitable for medical applications.

Comment on solubility

Solubility of 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenyl-butanoate

The solubility of 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenyl-butanoate (C14H22N2O2) is an important aspect to consider in various applications. This compound, characterized by its complex structure, exhibits moderate solubility in organic solvents. Here are some key points regarding its solubility:

  • Solvent Compatibility: It is generally more soluble in organic solvents such as ethanol and methanol compared to polar solvents like water.
  • Hydrophobic Nature: The presence of the bulky phenyl and diethylamino groups contributes to its hydrophobic characteristics, often leading to lower solubility in aqueous solutions.
  • Concentration Dependent: The solubility may increase with temperature, making higher temperatures favorable for dissolving the compound in specific solvents.

As a result, while the compound can be utilized in organic applications where solubility in non-polar or slightly polar solvents is advantageous, care should be taken when considering its use in aqueous formulations. Understanding these solubility behaviors is crucial for optimizing its application in pharmaceuticals and other chemical industries.

Interesting facts

Interesting Facts about 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenyl-butanoate

This compound, known as 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenyl-butanoate, falls into a fascinating category of chemical compounds with notable applications in the pharmaceutical industry. Here are some intriguing aspects worth exploring:

  • Therapeutic Potential: This compound may have promising effects in areas such as analgesia or as an anesthetic, largely due to its diethylamino moiety, which often imparts favorable pharmacological properties.
  • Chemical Versatility: The unique structure, featuring both an alkyl side chain and a diethylamino group, allows this compound to participate in various chemical reactions, such as esterification or nucleophilic substitution.
  • Structure-Activity Relationship (SAR): Scientists are often keen on understanding how the different functional groups influence the biological activity. Researching SAR can yield insights into optimizing compounds for better efficacy.
  • Potential Side Effects: Like many compounds that interact with biological systems, it is essential to study the side effects. Understanding these can help refine drug dosage and administration routes to minimize risks.

One of the most exciting aspects of studying compounds like this is the ongoing research that often leads to new discoveries. As the motto goes in science, "The more we learn, the more we realize how much we don't know." This highlights the importance of continuous exploration and examination within the realm of chemical compounds, especially those with potential therapeutic applications.

In summary, 2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenyl-butanoate serves as a prime example of how one compound can encapsulate a wealth of knowledge and possibilities in the field of chemistry. Further research may unveil even more about its capabilities and applications!

Synonyms
Oxeladin
468-61-1
Oxeladina
Oxeladine
Oxeladina [INN-Spanish]
2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate
Oxeladine [INN-French]
Oxeladinum [INN-Latin]
Oxeladinum
Oxeladin [INN:BAN:DCF]
Oxeladin tannate
2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate
EINECS 207-412-1
UNII-SNC1080T5Y
Oxeladin (INN)
BRN 2003403
SNC1080T5Y
Pectamol (Salt/Mix)
OXELADIN [INN]
OXELADIN [MI]
Ethanol, 2-(2-(diethylamino)ethoxy)-, 2-ethyl-2-phenylbutyrate
OXELADIN [WHO-DD]
2-Ethyl-2-phenylbutyric acid 2-(2-diethylaminoethoxy)ethyl ester
DTXSID0048343
2-(2-Diethylaminoethoxy)ethyl alpha,alpha-diethylphenylacetate
EC 207-412-1
4-09-00-01906 (Beilstein Handbook Reference)
alpha,alpha-Diethylbenzeneacetic acid 2-(2-(diethylamino)ethoxy)ethyl ester
BUTYRIC ACID, 2-ETHYL-2-PHENYL-, 2-(2-(DIETHYLAMINO)ETHOXY)ETHYL ESTER
Oxeladin tannate (JAN)
Oxeladin tannate [JAN]
Oxeladine (INN-French)
Oxeladinum (INN-Latin)
Oxeladina (INN-Spanish)
Benzeneacetic acid, .alpha.,.alpha.-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester
2-(2-DIETHYLAMINOETHOXY)-ETHYL 2-ETHYL-2-PHENYLBUTYRATE
2-(2-Diethylaminoethoxy)ethyl .alpha.,.alpha.-diethylphenylacetate
.alpha.,.alpha.-Diethylbenzeneacetic acid 2-(2-(diethylamino)ethoxy)ethyl ester
2-(2-(diethylamino)ethoxy)ethyl 2-ethyl-2-phenylbutanoate
Oxelaidin
PaxAladine
468-61-1, Oxeladin
MLS001047519
SCHEMBL405413
CHEMBL1500276
DTXCID1028318
R05DB09
CHEBI:135424
HMS2800D17
HMS3604M03
STL059065
AKOS005711563
DB04822
Benzeneacetic acid, alpha,alpha-diethyl-, 2-(2-(diethylamino)ethoxy)ethyl ester
NCGC00389219-01
NCGC00389219-02
SMR000425406
SBI-0207046.P001
NS00007663
D08310
AB00658553_05
AB00658553_06
EN300-18553895
Q4332778
BRD-K17977438-048-02-4
BRD-K17977438-048-03-2
BRD-K17977438-048-04-0
2-[2-(Diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate #
Butyric acid, 2-ethyl-2-phenyl-, 2-(2-(diethylamino)ethoxy)ethyl ester, tannate
2-Ethyl-2-phenyl-butyric acid 2-(2-diethylamino-ethoxy)-ethyl ester; compound with 3-carboxy-3-hydroxy-pentanedioic acid
207-412-1
Benzeneacetic acid, a,a-diethyl-, 2-[2-(diethylamino)ethoxy]ethyl ester; Butyric acid, 2-ethyl-2-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester (6CI,7CI,8CI); Ethanol, 2-(2-diethylaminoethoxy)-, 2-ethyl-2-phenylbutyrate (6CI); 2-(2-Diethylaminoethoxy)ethy