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Verapamil

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Identification
Molecular formula
C27H38N2O4
CAS number
52-53-9
IUPAC name
2-[2-(diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile
State
State

At room temperature, Verapamil is typically in a solid state, appearing as a crystalline solid or powder.

Melting point (Celsius)
127.50
Melting point (Kelvin)
400.65
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
454.60g/mol
Molar mass
454.6040g/mol
Density
1.0876g/cm3
Appearence

Verapamil typically appears as a white or off-white crystalline solid. It may also be available in powder form and can have a slightly characteristic odor.

Comment on solubility

Solubility Characteristics of 2-[2-(diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile

The solubility of 2-[2-(diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile can be quite intricate due to its complex structure, which includes multiple functional groups that influence its interaction with solvents.

Factors Influencing Solubility

  • Polarity: This compound has both polar and non-polar regions, making it soluble in a mix of polar and non-polar solvents.
  • Hydrogen Bonding: The presence of the diethylamino group allows for potential hydrogen bonding, which can enhance solubility in polar solvents like water.
  • Alkyl Chains: The long hydrophobic diethylamino chains introduce non-polar characteristics, which might hinder solubility in purely polar environments.

Common Solvents

Based on its chemical makeup, 2-[2-(diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile is likely to exhibit the following solubility behavior:

  • Soluble in organic solvents such as ethanol, methanol, and chloroform.
  • Poorly soluble in water due to the hydrophobic nature of the naphthyl group.

In conclusion, while the compound may show some solubility in polar solvents, its overall tendency due to non-polar components suggests a mixed solubility profile, making it important to select the appropriate solvent for practical applications.

Interesting facts

Interesting Facts about 2-[2-(Diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile

This intriguing compound, 2-[2-(diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile, is part of a larger family of organic compounds known as nitriles, which are characterized by the presence of a cyano group (-C≡N). Here are some fascinating aspects to consider:

  • Pharmaceutical Relevance: This compound possesses a unique structure that may contribute to its potential pharmacological activities. Compounds with similar structural motifs have been investigated for their roles as therapeutic agents in various diseases.
  • Structure-Activity Relationship: The presence of both diethylamino and naphthyl groups in its structure suggests interesting interactions with biological targets. Chemists often study these relationships to optimize drug efficacy and selectivity.
  • Organic Synthesis: The synthesis of this compound involves intricate organic chemistry techniques, showcasing the creativity and precision required in modern chemical laboratories. Techniques such as nucleophilic substitutions and coupling reactions can be key in forming its complex structure.
  • Mechanism of Action: While the precise biological mechanisms remain an area for research, compounds containing nitrile groups are known to affect neurotransmitter systems, making them a subject of interest in neurochemistry.

In the words of Victor Hugo, “Strength is an invincible force.” The study of compounds like this one represents the strength of chemistry to unlock new therapeutic possibilities and innovate within the pharmaceutical industry.


In conclusion: 2-[2-(diethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile serves as a prime example of how organic chemistry extends its impact into the realms of medicine and biology, paving the way for future discoveries!

Synonyms
BRN 2153892
2572-72-7
alpha-(2-(Diethylamino)ethyl)-alpha-isopropyl-1-naphthaleneacetonitrile
1-NAPHTHALENEACETONITRILE, alpha-(2-(DIETHYLAMINO)ETHYL)-alpha-ISOPROPYL-
DTXSID10948601
2-[2-(DIETHYLAMINO)ETHYL]-3-METHYL-2-(NAPHTHALEN-1-YL)BUTANENITRILE