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Disulfiram

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Identification
Molecular formula
C10H20N2S2
CAS number
97-77-8
IUPAC name
2-[2-(diethylamino)ethyldisulfanyl]-N,N-diethyl-ethanamine;dihydrochloride
State
State

Disulfiram is typically in a solid state at room temperature. It is often supplied in the form of tablets or powders for medical and laboratory use.

Melting point (Celsius)
71.00
Melting point (Kelvin)
344.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
297.55g/mol
Molar mass
297.5460g/mol
Density
1.2510g/cm3
Appearence

Disulfiram appears as a white to off-white crystalline powder. It is odorless and tasteless when pure, but may have a faint sulfurous odor due to impurities. The substance is often formulated with ethanol to slow down the evaporation process in its therapeutic preparations.

Comment on solubility

Solubility Characteristics of 2-[2-(diethylamino)ethyldisulfanyl]-N,N-diethyl-ethanamine; dihydrochloride

The solubility of 2-[2-(diethylamino)ethyldisulfanyl]-N,N-diethyl-ethanamine; dihydrochloride is an important consideration in its applications and handling. This compound, due to the presence of a dihydrochloride salt form, exhibits certain characteristics:

  • Highly Soluble in Water: Being a salt, it is generally expected to be highly soluble in polar solvents, particularly water.
  • Impact of Temperature: The solubility can increase with temperature, making it crucial for processes that involve heating.
  • Effect of pH: Variations in pH can influence solubility; for instance, increasing acidity may enhance solubility due to protonation of the amine groups.
  • Limited Solubility in Organic Solvents: The presence of long hydrocarbon chains may limit solubility in non-polar organic solvents, making it more suitable for aqueous environments.

When handling or applying this compound, it is essential to remember that:

  1. Proper dissolution techniques should be employed to achieve the necessary concentration.
  2. Compatibility with solvents must be evaluated to ensure effective use in chemical reactions.

Therefore, understanding the solubility profile of this dihydrochloride salt is key to optimizing its utilization in various chemical applications.

Interesting facts

Interesting Facts About 2-[2-(diethylamino)ethyldisulfanyl]-N,N-diethyl-ethanamine; dihydrochloride

This compound, known for its complex structure and intriguing properties, has garnered attention in the field of organic chemistry. Here are some remarkable aspects of this dihydrochloride form:

  • Diverse Applications: Due to its unique chemical properties, this compound is often explored for use in various fields such as medicinal chemistry and materials science.
  • Disulfanyl Functional Group: The presence of the disulfanyl (-S-S-) group is notable. Such groups are often linked to interesting redox chemistry, showcasing the ability to undergo oxidation and reduction reactions.
  • Biological Implications: Compounds containing diethylamino groups are known for their potential pharmacological activities, making them subjects of study in the development of new therapeutics.
  • Synthetic Route: The synthesis of this compound can involve multi-step processes, offering an excellent case study for those interested in organic synthesis techniques and strategies.
  • Stability: The dihydrochloride salt form is a strategy often used to enhance the stability and solubility of the compound. This is particularly useful in pharmaceutical applications.

In the words of a famous chemist, "Every compound tells a story" — and this dihydrochloride is no exception. From its intricate synthesis to its potential applications, it serves as a valuable example of the interplay between structure and function in chemical compounds.

As we continue to unveil the mysteries of such compounds, they remind us of the endless possibilities that exist within molecular chemistry.

Synonyms
22194-38-3
Tetraethylcystamine dihydrochloride
IGZ1ZP92B8
2,2'''-Dithiobis(triethylamine) dihydrochloride
Bis(beta-diethylaminoethyl)disulfide dihydrochloride
Ethanamine, 2,2'-dithiobis(N,N-diethyl-, dihydrochloride
2,2'-(Disulfane-1,2-diyl)bis(N,N-diethylethanamine) Dihydrochloride
AGN-PC-0JKLOP
UNII-IGZ1ZP92B8
CHEMBL1237384
DTXSID00274906
BIS(.BETA.-DIETHYLAMINOETHYL)DISULFIDE DIHYDROCHLORIDE
2-[2-(diethylamino)ethyldisulfanyl]-N,N-diethylethanamine;dihydrochloride