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Benzocaine

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Identification
Molecular formula
C9H11NO2
CAS number
94-09-7
IUPAC name
2-[2-(dimethylamino)-2-oxo-ethoxy]-N-[2-(dimethylamino)-2-oxo-ethyl]benzamide
State
State

At room temperature, benzocaine is a solid.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
165.19g/mol
Molar mass
165.1890g/mol
Density
1.0600g/cm3
Appearence

Benzocaine typically appears as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 2-[2-(dimethylamino)-2-oxo-ethoxy]-N-[2-(dimethylamino)-2-oxo-ethyl]benzamide

The solubility of 2-[2-(dimethylamino)-2-oxo-ethoxy]-N-[2-(dimethylamino)-2-oxo-ethyl]benzamide is influenced by several structural features and environmental conditions. Understanding its solubility profile is essential for applications in pharmaceutical formulations and chemical reactions. Here are some important aspects to consider:

  • Hydrophobic vs. Hydrophilic Interactions:
    Given that the compound contains both polar functional groups (like the amide and ethoxy groups) and hydrophobic aromatic components, it might exhibit moderate solubility in various solvents.
  • pH Sensitivity:
    The solubility can be significantly affected by the pH of the solvent. For example, the presence of protonated amine groups can enhance solubility in acidic conditions.
  • Solvent Compatibility:
    This compound may be expected to dissolve well in organic solvents such as dimethyl sulfoxide (DMSO) and to some degree in alcohols, while its solubility in water might be limited unless complicated with specific pH adjustments.
  • Temperature Dependence:
    Like many compounds, solubility can increase with temperature, making heat a possible method to facilitate dissolution in laboratory settings.

In conclusion, while predicting the exact solubility concisely might be challenging, general trends can guide expectations. Observations and experiments under varying conditions will provide deeper insights into the solubility characteristics of this compound.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)-2-oxo-ethoxy]-N-[2-(dimethylamino)-2-oxo-ethyl]benzamide

This compound, known for its remarkable structural complexity, is a member of the benzamide family and is distinguished by the presence of two dimethylamino functional groups. Here are some key highlights:

  • Versatile Applications: The unique chemical properties of this compound make it a potential candidate for use in pharmaceuticals, particularly in drug development. Its ability to interact with biological targets could lead to the formulation of innovative therapeutic agents.
  • Intriguing Structure: The incorporation of ethoxy and dimethylamino groups signifies a strategic design that enhances solubility and bioavailability, crucial parameters in medicinal chemistry.
  • Research Interest: Scientists are increasingly researching compounds like this for their roles in various biochemical pathways. Understanding their interactions at the molecular level may uncover novel biological mechanisms.
  • Potential Synthetic Routes: The synthesis of this compound can be a fascinating exploration in organic chemistry. Various synthetic methods might be employed, making it an excellent educational subject for students learning about reaction pathways.
  • Structure-Activity Relationship (SAR): This compound serves as a valuable example in the context of SAR studies. By modifying different aspects of its chemical structure, researchers can better predict how modifications affect biological activity.

In conclusion, 2-[2-(dimethylamino)-2-oxo-ethoxy]-N-[2-(dimethylamino)-2-oxo-ethyl]benzamide exemplifies the intersection of chemical innovation and biological application. Its multifaceted properties continue to captivate the scientific community, making it a fascinating subject for ongoing research and study.

Synonyms
6754-96-7
o-ANISAMIDE, alpha-(DIMETHYLCARBAMOYL)-N-((DIMETHYLCARBAMOYL)METHYL)-
DTXSID80217871
alpha-(Dimethylcarbamoyl)-N-((dimethylcarbamoyl)methyl)-o-anisamide
Benzamide, o-((dimethylcarbamoyl)methoxy)-N-((dimethylcarbamoyl)methyl)-
DTXCID30140362
SGMM