Skip to main content

Ethopropazine

ADVERTISEMENT
Identification
Molecular formula
C20H25N2O2S
CAS number
91-68-9
IUPAC name
2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate
State
State

At room temperature, Ethopropazine is typically in a solid state.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
356.50g/mol
Molar mass
356.5010g/mol
Density
1.2220g/cm3
Appearence

Ethopropazine typically appears as an off-white to pale beige crystalline powder. Its solid form can be slightly hygroscopic, meaning it may absorb moisture from the surrounding environment.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate

The solubility of 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate can be influenced by various factors, including its molecular structure and the presence of functional groups. Here are some key points to consider:

  • Polarity: The compound has both hydrophilic (e.g., the dimethylamino and carboxylate groups) and hydrophobic (phenothiazine structure) characteristics, which can create a complex interaction with solvent molecules.
  • Solvent Type: Typically, this compound may have better solubility in polar solvents such as ethanol or methanol due to the ability of these solvents to stabilize polar functional groups.
  • Temperature Dependency: Like many organic compounds, its solubility may increase with temperature, potentially allowing it to dissolve more readily in higher temperatures.
  • pH Sensitivity: The presence of the carboxylate group suggests that its solubility can be influenced by the pH of the solution, where increased acidity can enhance solubility.

In conclusion, while empirical data on the solubility of 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate in various solvents is essential for specific applications, understanding these fundamental principles can provide insights into its potential for use in chemical processes and formulations.

Interesting facts

Exploring 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate

2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate is a fascinating compound that belongs to the phenothiazine family, well-known for its diverse pharmacological properties. This compound provides an interesting case study for chemists and students alike:

  • Phenothiazine Backbone: The phenothiazine parent structure has historically been influential in the development of antipsychotic medications, making compounds in this class crucial in pharmacology.
  • Functional Group Diversity: The dimethylamino and carboxylate functional groups enhance the solubility and bioavailability of this compound, which is significant when exploring its therapeutic applications.
  • Bioactivity: Compounds containing phenothiazine structures are known to exhibit antipsychotic, antihistaminic, and antiemetic effects, making this compound a potential candidate for further research in medicinal chemistry.
  • Structure-Activity Relationship: The intricate design of this compound highlights the importance of structure-activity relationships (SAR) in drug development. Modifying the side chains can lead to variations in biological activity.
  • Research Applications: Being a derivative of phenothiazine, this compound is often studied in the context of its interaction with neurotransmitter systems, potentially offering insights into treating mental health disorders.

In conclusion, studying 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate not only uncovers the chemical intricacies of its structure but also opens the door to understanding its role in pharmacology and medicinal chemistry. As noted by researchers, "the evolution of pharmacologically active compounds continues to inspire novel treatments and therapies."

Synonyms
Dimethoxanate
Dimetoxanato
Dimethoxanatum
UNII-1E3KG5FWDB
1E3KG5FWDB
Dimethoxanate [INN:BAN]
Dimethoxanatum [INN-Latin]
Dimetoxanato [INN-Spanish]
Dimethoxanate (INN)
EINECS 207-520-9
DIMETHOXANATE [MI]
DIMETHOXANATE [INN]
DIMETHOXANATE [WHO-DD]
DTXSID50197257
2-(2-Dimethylaminoethoxy)ethyl 10-phenothiazincarboxylat
2-(2-Dimethylaminoethoxy)ethyl 10-phenothiazincarboxylat [IUPAC]
10H-Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester
Dimethoxanatum (INN-Latin)
Dimetoxanato (INN-Spanish)
2-(2-Dimethylaminoethoxy)ethyl phenothiazine-10-carboxylate
2-(2-(Dimethylamino)ethoxy)ethyl 10H-phenothiazine-10-carboxylate
2-(2-Dimethylaminoethoxy)ethyl 10-phenothiazincarboxylat (IUPAC)
2-[2-(dimethylamino)ethoxy]ethyl 10H-phenothiazine-10-carboxylate
DTXCID60119748
R05DB28
207-520-9
477-93-0
Cotrane; Tussidin
2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate
SCHEMBL1642409
CHEMBL2110862
CHEBI:135517
OOVJCSPCMCAXEX-UHFFFAOYSA-N
DB13794
FD159416
NS00006617
D07397
Q5277306