Interesting facts
Interesting Facts About 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate; hydrochloride
2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate; hydrochloride is a fascinating compound that belongs to the class of phenothiazines, which have a rich history in medicinal chemistry. Here are some intriguing aspects of this compound:
- Medicinal Applications: Phenothiazine derivatives, including this compound, have historically been used as antipsychotic agents. They act on neurotransmitter systems in the brain, specifically targeting dopamine receptors, which is critical for their therapeutic effects.
- Structure-Activity Relationship: The unique structure of this compound, characterized by the incorporation of a dimethylamino group and an ethoxy chain, plays a crucial role in its biological activity. Modifications in the phenothiazine core can lead to significant changes in pharmacological properties.
- Versatile Interactions: Due to the presence of multiple functional groups, this compound can engage in various chemical interactions, enhancing its potential as a versatile lead compound in drug development.
- Research Potential: Ongoing research into phenothiazine derivatives focuses on their potential in treating a range of conditions beyond psychiatric disorders, including anti-inflammatory and antimicrobial effects. Scientists are continually exploring new ways to modify these compounds for improved efficacy.
- Importance of Hydrochloride Form: The hydrochloride salt form often enhances the solubility and stability of the parent compound, making it more suitable for pharmacological applications. This is particularly important for oral and parenteral formulations.
As students and researchers delve into the world of organic and medicinal chemistry, the exploration of compounds like this one showcases the intricate balance of structure and function that is pivotal in developing new therapeutic agents. As quoted by renowned chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” This compound is a testament to that philosophy in the realm of medicinal chemistry.
Synonyms
DIMETHOXANATE HYDROCHLORIDE
Tussizid
518-63-8
Perlatos
Catrane
Dimethoxanate HCl
Dimetoxanate hydrochloride
Cotrane
Atuss
Dimethoxanate monohydrochloride
UNII-N5I6SR31GJ
EINECS 208-255-1
N5I6SR31GJ
NSC 169183
NSC-169183
Atuss (TN)
10H-Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester, monohydrochloride
Ethanol, 2-(2-(dimethylamino)ethoxy)-, phenothiazine-10-carboxylate (ester), hydrochloride
Phenothiazine-10-carboxylic acid 2-(2-(dimethylamino)ethoxy)ethyl ester hydrochloride
DTXSID30199734
2-(2-Dimethylaminoethoxy)ethyl phenothiazine-10-carboxylate hydrochloride
beta-Dimethylaminoethoxyethyl phenothiazine-10-carboxylate hydrochloride
2-(2-(Dimethylamino)ethoxy)ethyl phenothiazine-10-carboxylate hydrochloride
DIMETHOXANATE HYDROCHLORIDE [MART.]
DIMETHOXANATE HYDROCHLORIDE [WHO-DD]
Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester, monohydrochloride
2-[2-(Dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate hydrochloride
DIMETHOXANATE HYDROCHLORIDE (MART.)
Phenothiazine-10-carboxylic acid 2-[2-(dimethylamino)ethoxy]ethyl ester hydrochloride
DTXCID90122225
10H-Phenothiazine-10-carboxylic acid, 2-(2-(dimethylamino)ethoxy)ethyl ester, monohydrochloride (9CI)
208-255-1
Cothera
2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate;hydrochloride
SCHEMBL4418926
CHEMBL2106376
ZJRHNNNACBPWEB-UHFFFAOYSA-N
NSC169183
2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate,hydrochloride
NS00080528
D07850
WLN: T C666 BN ISJ BVO2O2N1&1 &GH
Q27284577
1OH-Phenothiazine-10-carboxylic acid, monohydrochloride
Ethanol, phenothiazine-10-carboxylate (ester), hydrochloride
2-[(Dimethylamino)ethoxy]ethyl 10-phenothiazinecarboxylate hydrochloride
Phenothiazine, beta-dimethylaminoethoxyethyl-10-carboxylate-, hydrochloride
.beta.-[(Dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate hydrochloride
Solubility of 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate; hydrochloride
The solubility of 2-[2-(dimethylamino)ethoxy]ethyl phenothiazine-10-carboxylate; hydrochloride is an intriguing subject, primarily due to its chemical structure and functional groups. Understanding its solubility can help in determining its biological activity and potential applications.
General Characteristics:
In practical terms:
As a rule of thumb, "like dissolves like", so ensuring that the solvent used has similar polar characteristics will generally yield better solubility for this compound. The intricate balance between its chemical structure and the environment in which it is dissolved leads to exciting opportunities in both research and application.