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Ibuprofen nitrile

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Identification
Molecular formula
C20H29NO
CAS number
63195-53-7
IUPAC name
2-[2-(dimethylamino)ethyl]-2-(4-isobutylphenyl)-3-methyl-butanenitrile
State
State

At room temperature, ibuprofen nitrile is a liquid. It remains stable under normal conditions of use and storage.

Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
275.46g/mol
Molar mass
275.4280g/mol
Density
0.9445g/cm3
Appearence

Ibuprofen nitrile typically appears as a colorless to pale yellow liquid. It may have a faint, characteristic aromatic odor associated with its chemical structure.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-2-(4-isobutylphenyl)-3-methyl-butanenitrile

The solubility of the compound 2-[2-(dimethylamino)ethyl]-2-(4-isobutylphenyl)-3-methyl-butanenitrile exhibits some fascinating characteristics due to its unique structural features. The solubility behavior can be influenced by several factors:

  • Polarity: The presence of the dimethylamino functional group contributes to a degree of polarity, which can enhance solubility in polar solvents like water.
  • Hydrophobicity: The isobutylphenyl group introduces hydrophobic characteristics, making the compound more soluble in organic solvents such as ethanol, acetone, and chloroform.
  • Steric Effects: The branched structure may create steric hindrance, potentially affecting how the compound interacts with solvents, influencing its solubility.
  • Concentration Levels: At higher concentrations, the solubility may vary significantly due to intermolecular interactions.

Therefore, it is essential to consider the medium when evaluating solubility. The multitude of interactions can lead to varied solubility results; for instance, in a polar environment, the solubility may not be as pronounced due to competing solvation effects.

In conclusion, while it may have some soluble properties in polar solvents due to its dimethylamino group, its hydrophobic regions make it more favorable in non-polar environments. The solubility of this compound is a reflection of its dual nature, balancing between hydrophilic and hydrophobic characteristics.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)ethyl]-2-(4-isobutylphenyl)-3-methyl-butanenitrile

This compound, commonly referenced in the field of medicinal chemistry, is notable for its intriguing structural features and potential applications. Here are some fascinating details:

  • Versatile Applications: Compounds with a similar structure are often explored for their usefulness in pharmaceuticals, particularly as therapeutic agents.
  • Complex Structure: The presence of a dimethylamino group suggests this compound can interact with biological systems effectively, providing sites for potential receptor binding.
  • Research Interest: Its synthesis and reactivity have caught the attention of researchers, aiming to develop new drugs that target specific pathways in human diseases.
  • Isomer Importance: The unique isobutylphenyl segment within the compound indicates that isomers may exhibit different pharmacological properties, making structural studies crucial.
  • Potential for Modification: The presence of various functional groups may allow for *chemical modifications* that can tailor its properties for specific applications, enhancing its effectiveness.

As a compound, 2-[2-(dimethylamino)ethyl]-2-(4-isobutylphenyl)-3-methyl-butanenitrile serves as an exemplary model for illustrating the connection between chemistry and drug design. Its unique features present exciting opportunities for further exploration and innovation in the field.

Synonyms
BRN 2135135
4-(Dimethylamino)-2-(p-isobutylphenyl)-2-isopropylbutyronitrile
14780-14-4
alpha-Isopropyl-alpha-(2-dimethylaminoethyl)-p-isobutylphenylacetonitrile
BUTYRONITRILE, 4-(DIMETHYLAMINO)-2-(p-ISOBUTYLPHENYL)-2-ISOPROPYL-
DTXSID30933216
2-[2-(dimethylamino)ethyl]-3-methyl-2-[4-(2-methylpropyl)phenyl]butanenitrile