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Propafenone

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Identification
Molecular formula
C21H27NO
CAS number
34183-22-7
IUPAC name
2-[2-(dimethylamino)ethyl]-2-(4-isopropylphenyl)-3-methyl-butanenitrile
State
State

At room temperature, propafenone is typically found in its solid form as a crystalline hydrochloride salt, facilitating its use in pharmaceutical preparations.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
407.80
Boiling point (Kelvin)
680.95
General information
Molecular weight
341.47g/mol
Molar mass
341.4710g/mol
Density
1.0600g/cm3
Appearence

Propafenone hydrochloride appears as a white, crystalline solid with no characteristic odor.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-2-(4-isopropylphenyl)-3-methyl-butanenitrile

The solubility of 2-[2-(dimethylamino)ethyl]-2-(4-isopropylphenyl)-3-methyl-butanenitrile in various solvents is an important consideration in its practical uses. This compound, possessing a complex structure, can exhibit distinct solubility characteristics due to its various functional groups, including the nitrile moiety and a dimethylamino group.

Solubility Overview

Key points regarding the solubility of this compound include:

  • Polar Solvents: The presence of the nitrile group may enhance solubility in polar solvents such as water and methanol.
  • Non-Polar Solvents: Due to its bulky isopropylphenyl group, the compound is likely to demonstrate significant solubility in non-polar organic solvents like hexane or toluene.
  • Temperature Effects: Solubility may increase with temperature, especially in solid forms.

It's critical to note that solubility varies with concentration and specific solvent interactions. One might find that:

  • The compound is soluble at lower concentrations but may precipitate as saturation is reached in certain solvents.
  • Interactions between solvent molecules and the dimethylamino group play a significant role in affecting solubility patterns.

In summary, while 2-[2-(dimethylamino)ethyl]-2-(4-isopropylphenyl)-3-methyl-butanenitrile showcases a balance of polar and non-polar characteristics, understanding its solubility in various environments is essential for optimal applications and handling. Experimentation is often required to ascertain precise solubility data.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)ethyl]-2-(4-isopropylphenyl)-3-methyl-butanenitrile

This compound, often referred to through its abbreviated structure, is notable for its intriguing chemical properties and potential applications in various fields. Here are some interesting insights:

1. Structural Composition

  • The compound contains a complex structure with multiple functional groups, including a nitrile and an amine.
  • Its unique arrangement allows it to exhibit both hydrophobic and hydrophilic characteristics, making it suitable for diverse chemical environments.

2. Biological Significance

  • Research has indicated that compounds containing the dimethylamino group may exhibit significant biological activity, particularly in medicinal chemistry.
  • This compound could serve as a framework for developing pharmaceuticals targeting specific biological pathways.

3. Synthesis and Production

  • The synthesis of this compound typically involves multi-step reactions, showcasing the intricate nature of organic synthesis.
  • Chemists can utilize various methods, including nucleophilic substitutions and functional group transformations, to generate this compound in the laboratory.

4. Application Potential

  • The presence of the nitrile group is particularly advantageous, as nitriles are known for their versatile reactivity in organic synthesis.
  • This compound may find use in the development of agrochemicals, colorants, or even advanced materials.

In conclusion, 2-[2-(dimethylamino)ethyl]-2-(4-isopropylphenyl)-3-methyl-butanenitrile is not just a chemical compound but a potential key player in the realm of organic chemistry and its application in various industries.

Synonyms
BRN 2127925
2-(p-Cumenyl)-4-(dimethylamino)-2-isopropylbutyronitrile
14780-13-3
BUTYRONITRILE, 2-(p-CUMENYL)-4-(DIMETHYLAMINO)-2-ISOPROPYL-
DTXSID70933215
2-[2-(dimethylamino)ethyl]-3-methyl-2-[4-(propan-2-yl)phenyl]butanenitrile