Skip to main content

Nefazodone

ADVERTISEMENT
Identification
Molecular formula
C25H32N2O2
CAS number
83366-66-9
IUPAC name
2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile
State
State

At room temperature, Nefazodone is in the form of a crystalline solid.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
470.15
Boiling point (Kelvin)
743.30
General information
Molecular weight
470.65g/mol
Molar mass
470.6530g/mol
Density
1.1253g/cm3
Appearence

Nefazodone appears as a white to off-white crystalline powder. It may have characteristic odor based on its formulation.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile

The solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile, often referred to with its IUPAC name for brevity, can be influenced by several factors due to its complex structure:

  • Polarity: The presence of the dimethylamino group may enhance solubility in polar solvents but might limit its solubility in non-polar solvents.
  • Hydrophobic Character: The naphthyl group lends a hydrophobic property, which could affect solubility in aqueous environments.
  • Temperature Dependence: Higher temperatures typically increase solubility for many organic compounds. It is crucial to assess the solubility at different temperatures.
  • Solvent Specificity: This compound may dissolve well in organic solvents such as ethanol, methanol, or chloroform but may show limited solubility in water.

It’s important to note that while some organic compounds exhibit predictable solubility patterns, the unique combination of functional groups in this compound can lead to unexpected solubility behavior. Researchers often utilize solubility data to inform appropriate solvent selection for reactions and applications.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile

This fascinating compound, known for its complex structure and properties, belongs to a class of compounds that often exhibit significant biological activity. Here are some intriguing aspects of this molecule:

  • Applications in Medicine: This compound has potential implications in pharmacology, particularly within the realm of neurology and psychiatry. Its interaction with neurotransmitter systems could pave the way for innovative treatments.
  • Structure-Activity Relationship: The presence of both a dimethylamino group and a naphthyl moiety suggests that its activity can be influenced by variations in its structure. Exploring these changes can lead to the development of more effective compounds.
  • Complexity: The structure of this compound is a perfect example of molecular complexity, incorporating multiple functional groups, which contributes to its diverse chemical behavior and reactivity.
  • Research Potential: Scientists are particularly interested in exploring its potential as a lead compound for synthesizing novel pharmaceuticals, demonstrating that compounds of this nature can be more than just intriguing structures.
  • Historical Significance: Compounds like this have often contributed to our understanding of molecular interactions and the design of drugs, emphasizing their importance in the development of medicinal chemistry.

In summary, 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)butanenitrile not only showcases the beauty of organic chemistry through its intricate structure but also highlights the potential it holds for pharmaceutical advancements. As research in this area progresses, who knows what exciting discoveries await us in the future?

Synonyms
1425-60-1
BRN 2143184
alpha-(2-(Dimethylamino)ethyl)-alpha-isopropyl-1-naphthaleneacetonitrile
1-NAPHTHALENEACETONITRILE, alpha-(2-(DIMETHYLAMINO)ETHYL)-alpha-ISOPROPYL-
alpha-[2-(Dimethylamino)ethyl]-alpha-isopropyl-1-naphthaleneacetonitrile
2-[2-(dimethylamino)ethyl]-3-methyl-2-naphthalen-1-ylbutanenitrile
DTXSID70931493
2-[2-(dimethylamino)ethyl]-3-methyl-2-(naphthalen-1-yl)butanenitrile