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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)pentanoic acid
State
State

At room temperature, naproxen is in a solid state.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
430.00
Boiling point (Kelvin)
703.15
General information
Molecular weight
230.32g/mol
Molar mass
230.3170g/mol
Density
1.2670g/cm3
Appearence

Naproxen typically appears as a crystalline solid. It is often white or off-white in color and is odorless.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)pentanoic acid

The solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)pentanoic acid, often referred to as a complex organic compound, can be influenced by several factors typical of amino acids and their derivatives:

  • Solvent Polarity: This compound tends to exhibit better solubility in polar solvents due to the presence of the dimethylamino group, which can form hydrogen bonds.
  • pH Levels: The carboxylic acid functional group can significantly affect solubility; at lower pH levels, it may exist in its protonated form, influencing its interaction with water.
  • Temperature: Typically, an increase in temperature can enhance solubility in organic compounds, leading to more effective dissolution.
  • Substituent Effects: The bulky naphthyl group might hinder solubility in certain non-polar solvents while enhancing it in more polar environments.

In summary, one might state that "the solubility profile of this compound is multifaceted, influenced by both its structural characteristics and the environment in which it is tested." Therefore, a careful evaluation with respect to various solvents and conditions is necessary to derive its complete solubility behavior.

Interesting facts

Interesting Facts about 2-[2-(Dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)pentanoic Acid

This fascinating compound, commonly known as a derivative of amino acids, belongs to a class of substances that plays a significant role in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Pharmacological Potentials: Compounds of this nature are researched for their potential applications in pharmacology, particularly in designing drugs that can interact with specific receptors in the human body.
  • Structural Diversity: The presence of the 1-naphthyl group provides unique structural and electronic properties that can influence the compound's biological activity.
  • Dimethylamino Functionality: The dimethylamino group enhances the lipophilicity of the molecule, potentially aiding in membrane penetration and increasing its efficacy in biological systems.
  • Research Applications: This compound, like many similar amino acid derivatives, is often used in research to understand mechanisms of action of neurotransmitters and how they relate to mental health.
  • Synthetic Pathways: The synthesis of such complex molecules often involves multi-step reactions, showcasing the creativity and precision required in organic chemistry.

As a study subject, 2-[2-(dimethylamino)ethyl]-3-methyl-2-(1-naphthyl)pentanoic acid illustrates the intricate balance between structural complexity and functional potential, making it a compelling area of study for aspiring chemists and pharmacologists alike.

In the words of a renowned chemist, “The beauty of chemistry lies not only in its fundamental principles but also in the endless possibilities derived from the manipulation of molecular structures.” This compound truly embodies that sentiment.