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Venlafaxine

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Identification
Molecular formula
C17H27NO
CAS number
93413-69-5
IUPAC name
2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile
State
State

At room temperature, Venlafaxine is generally in a solid state. It is often formulated as tablets or capsules for medicinal use.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
582.40
Boiling point (Kelvin)
855.55
General information
Molecular weight
277.40g/mol
Molar mass
277.4020g/mol
Density
1.0480g/cm3
Appearence

Venlafaxine typically appears as a white to off-white crystalline solid. It is usually found in its hydrochloride salt form for pharmaceutical use.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile

The solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile can be intriguing due to its complex structure. This organic compound exhibits notable characteristics in various solvents.

  • Polar Solvents: Compounds similar to this one tend to be moderately soluble in polar solvents such as water, methanol, or ethanol. The presence of the dimethylamino group enhances polar interactions.
  • Non-polar Solvents: Conversely, it shows higher solubility in non-polar solvents, including hexane and chloroform, due to the larger naphthyl moiety which increases hydrophobicity.
  • Temperature Dependence: As with many organic compounds, solubility can vary significantly with temperature; generally, increasing temperature enhances solubility.

In summary, the solubility behavior of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile is dictated by its molecular structure, which influences its interactions with different solvent environments. Understanding these interactions is crucial for applications in synthesis and formulation.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile

The compound 2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile is quite intriguing to chemists due to its unique structure and properties. Here are some fascinating aspects of this compound:

  • Structural Complexity: The compound features a branched alkyl structure with a naphthalene group, which contributes to its interesting physical and chemical properties. The presence of a nitrile group further adds to its reactivity and potential applications in organic synthesis.
  • Biological Activity: Compounds with similar structural motifs have been studied for various biological activities, making this one worth investigating for potential pharmaceutical uses. They may exhibit properties such as antimicrobial, anti-inflammatory, and even antitumor effects.
  • Research Applications: The combination of a dimethylamino group and naphthalene might grant this compound unique interactions with biological systems, prompting research in medicinal chemistry and drug design.
  • Synthesis and Derivatives: The synthesis of such compounds can be creatively approached using various organic methodologies. Researchers may also explore the synthesis of derivatives to enhance efficacy or reduce toxicity.
  • Chirality Considerations: Some derivatives of naphthyl compounds can display chirality, opening avenues for stereochemical studies that are critical in drug development.

As we delve deeper into the chemistry of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(2-naphthyl)butanenitrile, we uncover possibilities that extend beyond classroom learning. The exploration of this compound may lead to the development of novel therapeutics, emphasizing the important role of organic chemistry in advancing science and medicine.

Synonyms
3582-42-1
BRN 2749126
alpha-Isopropyl-alpha-(2-dimethylaminoethyl)-2-naphthylacetonitrile
Butyronitrile, 4-dimethylamino-2-isopropyl-2-(2-naphthyl)-
Butyronitrile, 2-(2-dimethylaminoethyl)-3-methyl-2-(2-naphthyl)-
2-NAPHTHALENEACETONITRILE, alpha-(2-(DIMETHYLAMINO)ETHYL)-alpha-ISOPROPYL-
DTXSID30957230
2-[2-(DIMETHYLAMINO)ETHYL]-3-METHYL-2-(NAPHTHALEN-2-YL)BUTANENITRILE