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Bupropion

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Identification
Molecular formula
C13H18ClNO
CAS number
34841-39-9
IUPAC name
2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanamide
State
State

At room temperature, bupropion is typically found as a solid, particularly in its pharmaceutical tablet form. The crystalline form is solid as well.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
401.00
Boiling point (Kelvin)
674.15
General information
Molecular weight
239.33g/mol
Molar mass
239.3320g/mol
Density
1.0520g/cm3
Appearence

Bupropion typically appears as a white or off-white crystalline powder. It is commonly supplied in tablet form for medical purposes, usually in various strengths for oral administration.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanamide

The solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanamide is an intriguing aspect of this complex compound. As a derivative of a secondary amide, its solubility can be influenced by a variety of factors:

  • Polarity: Given the presence of a dimethylamino group, this compound exhibits some polarity, which can facilitate interactions with polar solvents such as water.
  • Hydrophobic Interactions: The propylphenyl group enhances hydrophobic character, potentially reducing solubility in polar environments.
  • Temperature Effects: Generally, the solubility of organic compounds like this one can increase with temperature, which may allow for greater dissolution in various solvents.
  • pH Influence: As an amide, rearrangements in the protonation state of the compound may influence its solubility in different pH conditions.

In summary, while this compound may demonstrate a moderate degree of solubility in polar solvents, the balance between its hydrophilic and hydrophobic characteristics plays a crucial role. Therefore, an in-depth analysis using different solvents and conditions would be essential to accurately determine the solubility profile of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanamide.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanamide

This fascinating compound, often abbreviated as a specific class of amides, showcases the intriguing interplay of structure and function in chemistry. Here are some notable aspects:

  • Pharmacological Potential: Compounds like this one are often investigated for their potential therapeutic applications. The presence of a dimethylamino group, for example, can enhance lipid solubility, which may lead to improved bioavailability in pharmacological contexts.
  • Synthetic Versatility: The synthesis of this compound involves intricate organic reactions, making it a perfect candidate for exploring synthetic methodologies and reaction mechanisms.
  • Molecular Diversity: The unique structure of this compound—characterized by its branched alkyl chains—demonstrates how small variations in functional groups can lead to significant changes in biological activity and properties.
  • Chirality Considerations: The spatial arrangement of atoms in this compound introduces the possibility of chirality, which is crucial in medicinal chemistry where the activity of enantiomers can differ vastly.

This compound serves as a reminder of how chemistry allows us to design and manipulate molecular architecture to discover new compounds with desirable properties. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." Exploring complex compounds such as this can lead to numerous innovations in chemistry and beyond.

In conclusion, the study of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanamide not only provides insight into functional groups and molecular interactions but also invites us to delve deeper into the world of medicinal chemistry and compound development.

Synonyms
BRN 2132664
4-(Dimethylamino)-2-isopropyl-2-(p-propylphenyl)butyramide
14780-17-7
BUTYRAMIDE, 4-(DIMETHYLAMINO)-2-ISOPROPYL-2-(p-PROPYLPHENYL)-
DTXSID10933219
2-[2-(Dimethylamino)ethyl]-3-methyl-2-(4-propylphenyl)butanimidic acid