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Flecainide

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Identification
Molecular formula
C17H22N2
CAS number
54143-55-4
IUPAC name
2-[2-(dimethylamino)ethyl]-3-methyl-2-(p-tolyl)butanenitrile
State
State

At room temperature, Flecainide is a solid, typically as a crystalline powder.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.00
Boiling point (Celsius)
465.20
Boiling point (Kelvin)
738.30
General information
Molecular weight
265.38g/mol
Molar mass
265.3850g/mol
Density
1.0785g/cm3
Appearence

Flecainide is a white to off-white, crystalline powder. It is typically odorless and can have a slightly bitter taste due to its crystalline nature.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(p-tolyl)butanenitrile

The solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-(p-tolyl)butanenitrile can be influenced by several factors due to its complex structure. This compound features both hydrophobic and hydrophilic regions, which can affect its interaction with solvents. Here are some key points to consider:

  • Polarity: The presence of the dimethylamino group endows the molecule with some polar characteristics, potentially enhancing its solubility in polar solvents.
  • Hydrophobic aromatic ring: The p-tolyl group introduces significant hydrophobicity, which can limit soluble interactions in polar solvents.
  • Solvent choice: It is likely to be more soluble in organic solvents such as dichloromethane or ethanol, but less soluble in water.
  • Temperature effect: Solubility may vary with temperature; for example, increased temperatures often enhance solubility in non-polar solvents.

In summary, while 2-[2-(dimethylamino)ethyl]-3-methyl-2-(p-tolyl)butanenitrile may exhibit some solubility characteristics in certain solvents, its overall solubility profile will heavily depend on the balance between its polar and non-polar components. Therefore, understanding the specific solvent environment is crucial for predicting its solubility.

Interesting facts

Interesting Facts about 2-[2-(dimethylamino)ethyl]-3-methyl-2-(p-tolyl)butanenitrile

This compound, often referred to in the context of medicinal chemistry, is known for its interesting structure and potential implications in pharmacology. It presents a unique combination of functional groups, making it a fascinating subject for study. Here are some key facts:

  • Structural Complexity: The presence of a dimethylamino group suggests that this compound may exhibit significant pharmacological activity. Amino groups are often key players in drug design due to their ability to form hydrogen bonds.
  • Potential Biological Activity: Compounds with similar frameworks have been investigated for their roles as neuromodulators and their effects on neurotransmitter systems, particularly in developing treatments for neurological disorders.
  • Research Interest: The unique combination of both p-tolyl and butanenitrile groups can lead to variations in biological activity. Researchers often explore such compounds for their therapeutic potential.
  • Synthetic Pathways: The complexity of synthesizing 2-[2-(dimethylamino)ethyl]-3-methyl-2-(p-tolyl)butanenitrile is an interesting challenge for chemists, requiring advanced techniques in organic synthesis and a deep understanding of reaction mechanisms.
  • Applications in Diverse Fields: Beyond pharmacology, such compounds can find applications in material science and organic electronics, showcasing their versatility in chemistry.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas," and this compound is certainly an example of the potential that can arise from thoughtful chemical design and exploration.

This compound embodies the spirit of inquiry in the field of organic chemistry, as it not only invites exploration of its structure and properties but also encourages researchers to uncover its multifaceted applications. The ongoing study of such compounds continues to enhance our understanding of chemical interactions and their implications in real-world applications.

Synonyms
BRN 2118635
4-(Dimethylamino)-2-isopropyl-2-p-tolylbutyronitrile
14780-11-1
BUTYRONITRILE, 4-(DIMETHYLAMINO)-2-ISOPROPYL-2-p-TOLYL-
DTXSID50933213
2-[2-(dimethylamino)ethyl]-3-methyl-2-(4-methylphenyl)butanenitrile