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Methadone

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Identification
Molecular formula
C21H27NO
CAS number
76-99-3
IUPAC name
2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile
State
State

At room temperature, Methadone is usually found as a solid or as a solution in liquid form when dissolved in water or alcohol.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
234.30
Boiling point (Kelvin)
507.45
General information
Molecular weight
309.45g/mol
Molar mass
309.4520g/mol
Density
0.9335g/cm3
Appearence

Methadone is a clear, colorless liquid when in solution form. As a solid, it appears as a white crystalline powder.

Comment on solubility

Solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile

The solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile in various solvents reveals important aspects of its chemical behavior. This compound, due to its specific functional groups and hydrophobic alkyl chain, exhibits varying degrees of solubility that can be outlined as follows:

  • Polar solvents: Limited solubility is expected in water, as the compound contains a hydrophobic aromatic ring combined with a long carbon chain, which tends to resist interaction with polar water molecules.
  • Non-polar solvents: Greater solubility should be observed in organic solvents such as hexane or toluene due to the non-polar characteristics of the alkyl and phenyl groups, allowing for better interactions and dissolution.
  • Protic solvents: The presence of the dimethylamino group may slightly enhance solubility in protic solvents (e.g., alcohols) due to potential hydrogen bonding, although overall solubility would still be moderate.

In conclusion, the solubility of 2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile is highly dependent on the nature of the solvent. Its amphiphilic nature may allow for some versatility in analysis and application:

  1. Generally poor solubility in water
  2. Better dissolution in non-polar organic solvents
  3. Moderate in protic solvents due to potential hydrogen bonding

Understanding the solubility of this compound is crucial for various applications, including chemical synthesis and biological interaction studies.

Interesting facts

Interesting Facts about 2-[2-(Dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile

This compound, often referred to in scientific circles as a member of the vast class of nitriles, showcases a fascinating array of chemical behaviors and applications. Chemists often find its structure intriguing due to the presence of both aromatic and aliphatic components, which result in unique properties. Here are some engaging insights about this compound:

  • Pharmaceutical Relevance: Compounds like 2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile are often explored for their potential roles in pharmacology, particularly as potential therapeutic agents. They can interact with biological systems in ways that are conducive to drug development.
  • Synthetic Pathways: The synthesis of this compound may involve several fascinating organic reactions, such as nucleophilic substitutions and functional group transformations, making it a captivating subject of study for organic chemists.
  • Chirality: The presence of chiral centers in its structure dictates that this compound can exist in multiple stereoisomeric forms, leading to distinct biological activities among its isomers. Such chirality plays an essential role in determining the efficacy and safety of medicinal compounds.
  • Characterization Techniques: Scientists employ various methods to identify and characterize 2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile, including NMR spectroscopy and mass spectrometry, to elucidate its structure and confirm its identity.

In summary, 2-[2-(dimethylamino)ethyl]-3-methyl-2-phenyl-butanenitrile is not merely a chemical compound, but rather a gateway into complex discussions about organic synthesis, biological interactions, and pharmaceutical applications. As you delve deeper into its study, remember that each aspect presented here contributes to a broader understanding of how organic compounds play pivotal roles in science and industry.

Synonyms
BRN 2808703
4-(Dimethylamino)-2-isopropyl-2-phenylbutyronitrile
2809-45-2
BUTYRONITRILE, 4-(DIMETHYLAMINO)-2-ISOPROPYL-2-PHENYL-
DTXSID00950819
2-[2-(dimethylamino)ethyl]-3-methyl-2-phenylbutanenitrile