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Phenacetin

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Identification
Molecular formula
C10H13NO2
CAS number
62-44-2
IUPAC name
2-(2-ethoxyanilino)-N,N-diethyl-acetamide
State
State

At room temperature, Phenacetin is in solid state, presenting as a white crystalline powder.

Melting point (Celsius)
134.50
Melting point (Kelvin)
407.65
Boiling point (Celsius)
515.20
Boiling point (Kelvin)
788.35
General information
Molecular weight
179.22g/mol
Molar mass
179.2160g/mol
Density
1.0998g/cm3
Appearence

Phenacetin appears as white, crystalline powder with no odor. It is somewhat soluble in water and more soluble in organic solvents like alcohol, ether, and chloroform.

Comment on solubility

Solubility of 2-(2-ethoxyanilino)-N,N-diethyl-acetamide

The solubility of 2-(2-ethoxyanilino)-N,N-diethyl-acetamide can be influenced by various factors, including its molecular structure and the presence of functional groups. This compound exhibits moderate solubility in organic solvents due to its polar ethoxy and amide groups.

Key Points on Solubility:

  • Polar Solvents: It is more soluble in polar organic solvents such as methanol and ethanol.
  • Non-Polar Solvents: Its solubility in non-polar solvents, like hexane, is significantly lower.
  • Temperature Dependence: Solubility may increase with temperature, following the general trend observed with similar amide compounds.
  • pH Influence: The solubility may also vary with pH, particularly if the compound can ionize; however, the specific behavior would need experimental verification.

In summary, while this compound shows a trend of solubility in polar environments, it is essential to consider the solvent characteristics and experimental conditions to attain precise solubility data. Understanding these factors can help predict its behavior in various chemical reactions and applications.

Interesting facts

Interesting Facts About 2-(2-ethoxyanilino)-N,N-diethyl-acetamide

2-(2-ethoxyanilino)-N,N-diethyl-acetamide is a fascinating chemical compound that carries with it a range of interesting properties and applications. Here are some key points to consider:

  • Structure and Function: The compound features an ethoxy group and a diethyl acetamide structure, which contributes to its unique chemical behavior. The presence of the aniline component indicates potential applications in pharmaceuticals and organic synthesis.
  • Biological Activity: Compounds like 2-(2-ethoxyanilino)-N,N-diethyl-acetamide may exhibit significant biological activity, making them candidates for research in medicinal chemistry. They could potentially interact with various biological systems, providing avenues for drug development.
  • Versatile Applications: Due to its structure, this compound may serve multiple roles in chemical processes, including as an intermediate in synthesis pathways or as a tool for molecular probes in biological studies.
  • Safety Considerations: As with many compounds, understanding the safety and toxicity profile of 2-(2-ethoxyanilino)-N,N-diethyl-acetamide is crucial for proper handling and application. Researchers must ensure that they follow appropriate safety protocols when working with this compound.
  • Importance in Research: This compound is a valuable subject of study, providing insight into the behavior of amide-containing compounds and their potential utilities across different fields of chemistry.

In summary, the combination of aniline derivatives and acetamide structures makes 2-(2-ethoxyanilino)-N,N-diethyl-acetamide not only interesting from a synthetic chemistry perspective but also significant in the context of pharmaceutical research and development.

Synonyms
ACETAMIDE, N,N-DIETHYL-2-(o-PHENETIDINO)-
15010-76-1
2-(2-ethoxyanilino)-N,N-diethylacetamide
FC 365
N,N-Diethyl-N'-(2-ethoxyphenyl)glycinamide [French]
1226 I.S.
N,N-Diethyl-N'-(2-ethoxyphenyl)glycinamide
NIOSH/AB7340000
DTXSID00164474
AKOS000252533
AB73400000
N,N-Diethyl-2-((2-ethoxyphenyl)amino)acetamide
Acetamide, N,N-diethyl-2-((2-ethoxyphenyl)amino)-