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Oxamic acid, (2-ethoxyphenyl)hydrazide

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Identification
Molecular formula
C12H14N2O4
CAS number
4358-63-2
IUPAC name
2-[(2-ethoxybenzoyl)hydrazono]propanoic acid
State
State

At room temperature, this compound is typically in a solid state. It can exhibit different crystalline structures depending on how it is processed and the conditions it is kept under, including humidity and temperature.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
286.00
Boiling point (Kelvin)
559.15
General information
Molecular weight
236.25g/mol
Molar mass
236.2480g/mol
Density
0.9110g/cm3
Appearence

The compound typically appears as a solid, often in the form of a crystalline powder. The color can range from off-white to pale yellow. It is important to note that specific appearance details can vary depending on the purity and form of the sample.

Comment on solubility

Solubility of 2-[(2-ethoxybenzoyl)hydrazono]propanoic acid

The solubility of 2-[(2-ethoxybenzoyl)hydrazono]propanoic acid can be described as follows:

  • Polarity: The compound contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) components, which affects its solubility in various solvents.
  • Solvent Interaction: It is typically more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) compared to water due to its aromatic and aliphatic structures.
  • pH Dependence: The solubility may also depend on the pH of the solution, as the carboxylic acid group can ionize, enhancing solubility in basic conditions.
  • Temperature: Like many organic compounds, solubility can increase with temperature; hence, heating the solvent may improve dissolution.

In summary, while 2-[(2-ethoxybenzoyl)hydrazono]propanoic acid exhibits limited solubility in water, it shows a favorable solubility profile in organic solvents, which suggests its potential applications in organic synthesis and pharmaceutical formulations.

Interesting facts

Interesting Facts about 2-[(2-ethoxybenzoyl)hydrazono]propanoic Acid

This intriguing compound, known as 2-[(2-ethoxybenzoyl)hydrazono]propanoic acid, exhibits a fascinating blend of organic functional groups that make it a subject of interest in various chemical research applications.

Chemical Structure and Properties

One of the notable features of this compound is its hydrazone linkage, which is formed between a hydrazine derivative and a carbonyl compound. This structural motif imparts unique reactivity and stability, leading to various interesting characteristics:

  • Reactivity: The presence of the hydrazone group allows for potential applications in condensation reactions and serves as a precursor for synthesizing other compounds.
  • Biological Activity: Compounds with hydrazone structure are often explored for their medicinal properties, including anti-cancer and anti-inflammatory activities.
  • Solubility Variability: The ethoxy group in its structure can affect solubility in different solvents, making this compound versatile in experimental setups.

Applications in Research

2-[(2-ethoxybenzoyl)hydrazono]propanoic acid also finds relevance in multidisciplinary fields:

  • Synthetic Chemistry: It can serve as a building block for synthesizing more complex organic molecules.
  • Pharmaceutical Development: The biological activities can inspire drug design, particularly in treatments targeting specific diseases.

In summary, 2-[(2-ethoxybenzoyl)hydrazono]propanoic acid is not just a simple compound, but a vital part of the research domain, contributing to innovation in both organic synthesis and medicinal applications. It highlights the beauty of chemistry, demonstrating how complex structures can result in diverse functionalities and uses.

Synonyms
Ruvazone
Ruvazonum
20228-27-7
O5U67O8927
o-Ethoxybenzoic acid (1-carboxyethylidene)hydrazide
DTXSID00864927
ruvazona
DTXCID60813390
pyruvic acid o-ethoxybenzoylhydrazone
pyruvic acid 2-ethoxybenzoylhydrazone
RefChem:180383
Ruvazone [INN]
2-[(2-ethoxybenzoyl)hydrazinylidene]propanoic acid
Ruvazon
Ruvazon [INN-Spanish]
Ruvazonum [INN-Latin]
UNII-O5U67O8927
Pyruvic acid, O-ethoxybenzoylhydrazone
BRN 2591488
o-Ethoxy-benzoyl-hydrazone of pyruvic acid
o-Etossi-benzoil-idrazone dell'acido piruvico
M 6/42
2-Ethoxybenzoic acid (1-carboxyethylidene)hydrazide
SCHEMBL2109426
Benzoic acid, 2-ethoxy-, (1-carboxyethylidene)hydrazide
o-Etossi-benzoil-idrazone dell'acido piruvico [Italian]
BENZOIC ACID, o-ETHOXY-, (1-CARBOXYETHYLIDENE)HYDRAZIDE
NS00123738
Q27285371