Skip to main content

Orphenadrine

ADVERTISEMENT
Identification
Molecular formula
C18H23NO
CAS number
83-98-7
IUPAC name
2-[2-ethyl-1-(o-tolyl)cyclohexoxy]-N,N-dimethyl-ethanamine
State
State

At room temperature, Orphenadrine exists as a solid, typically in the form of crystalline powder or tablets.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
311.00
Boiling point (Kelvin)
584.15
General information
Molecular weight
269.39g/mol
Molar mass
269.4080g/mol
Density
1.0220g/cm3
Appearence

Orphenadrine is typically a white, crystalline powder. It may also be available in tablet form where it appears as white or off-white tablets. The compound is known for its distinct structure involving a cyclohexylamine constituent which adds to its appearance as a slightly thick crystalline substance.

Comment on solubility

Solubility of 2-[2-ethyl-1-(o-tolyl)cyclohexoxy]-N,N-dimethyl-ethanamine

The solubility of 2-[2-ethyl-1-(o-tolyl)cyclohexoxy]-N,N-dimethyl-ethanamine can be discussed through various considerations:

  • Polarity: This compound features both hydrophobic and hydrophilic characteristics, which might influence its solubility in different solvents.
  • Solvent Interaction: It is more likely to be soluble in organic solvents such as ethanol, acetone, or dichloromethane due to its overall structure.
  • Aqueous Solubility: Due to the presence of an amine group, the compound might have some degree of solubility in water, although this is likely limited.
  • Functional Groups: The presence of ether and amine functional groups can affect intermolecular interactions, influencing solubility patterns.

In conclusion, while 2-[2-ethyl-1-(o-tolyl)cyclohexoxy]-N,N-dimethyl-ethanamine exhibits the potential for solubility in specific organic solvents, its water solubility may be modest. As the saying goes, “like dissolves like,” which encapsulates the key principle in determining the solubility based on matching polarities of solute and solvent.

Interesting facts

Interesting Facts about 2-[2-ethyl-1-(o-tolyl)cyclohexoxy]-N,N-dimethyl-ethanamine

This compound presents a fascinating intersection of organic chemistry and pharmacology, characterized by its unique structure and potential applications. Here are some notable points:

  • Structure Complexity: The compound features a cyclohexane ring and an ethyl group, creating a steric environment conducive to specific interactions with biological targets.
  • Functional Groups: The presence of both dimethylamine and an ether link significantly influences its reactivity and biological activity. These functional groups are often associated with neurotransmitter systems in the body.
  • Potential Applications: Compounds with similar structures have been examined for their roles in drug development, especially in targeting the central nervous system and modulating neurotransmitter activity.
  • Synthesizing Challenges: The synthetic pathways for such complex structures can involve multiple steps, requiring careful planning to achieve high yields and pure products.
  • Analytical Techniques: Chemists often utilize NMR (Nuclear Magnetic Resonance) and Mass Spectrometry to analyze and confirm the composition of compounds like this, ensuring their purity and structural integrity.

In summary, 2-[2-ethyl-1-(o-tolyl)cyclohexoxy]-N,N-dimethyl-ethanamine is not only a captivating compound due to its intricate structure but also a subject of interest in medicinal chemistry for its biochemical properties and potential applications. Its study embodies the excitement of exploration in the chemical sciences.

Synonyms
AM-814/41093254
N-(2-{[2-ethyl-1-(2-methylphenyl)cyclohexyl]oxy}ethyl)-N,N-dimethylamine