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Flecainide

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Identification
Molecular formula
C17H23F2N3O
CAS number
54143-55-4
IUPAC name
2-[2-[ethyl(methyl)amino]ethyl]-3-methyl-2-(1-naphthyl)butanenitrile
State
State

Flecainide is typically found in a solid state at room temperature. It is often prepared in this form for pharmaceutical formulations.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.15
Boiling point (Celsius)
353.50
Boiling point (Kelvin)
626.65
General information
Molecular weight
415.55g/mol
Molar mass
415.5460g/mol
Density
1.1730g/cm3
Appearence

Flecainide appears as a white or off-white crystalline powder. It is known to be odorless and has a bitter taste. The powder is typically used in its pure crystalline form.

Comment on solubility

Solubility of 2-[2-[ethyl(methyl)amino]ethyl]-3-methyl-2-(1-naphthyl)butanenitrile

The solubility of 2-[2-[ethyl(methyl)amino]ethyl]-3-methyl-2-(1-naphthyl)butanenitrile can be influenced by several factors, including its molecular structure, polarity, and the temperature of the solvent. Here are several key points to consider:

  • Polarity: The presence of the ethyl(methyl)amino group may increase the compound's overall polarity, potentially enhancing its solubility in polar solvents such as water.
  • Hydrophobic interactions: However, the inclusion of the naphthyl group introduces significant hydrophobic characteristics, which could lead to reduced solubility in polar environments.
  • Temperature dependency: Solubility can vary with temperature; higher temperatures often increase solubility for many organic compounds, so performing solubility tests at different temperatures is essential.

In general, it is important to note that “the solubility of a compound is a complex interplay of multiple factors,” and in practical applications, experiments should be conducted to ascertain the exact solubility characteristics of this compound.

Understanding these factors will help in predicting the behavior of 2-[2-[ethyl(methyl)amino]ethyl]-3-methyl-2-(1-naphthyl)butanenitrile in various solvents and conditions.

Interesting facts

Interesting Facts about 2-[2-[ethyl(methyl)amino]ethyl]-3-methyl-2-(1-naphthyl)butanenitrile

This complex compound, often referred to simply by its functional groups, is an example of a polyfunctional organic molecule known for its intriguing properties and potential applications in medicinal chemistry. Here are some engaging aspects to consider:

  • Pharmacological Relevance: Compounds like this one may exhibit significant biological activity, potentially affecting neurotransmitter systems and offering insights into drug design, especially in the realm of neuropharmacology.
  • Synthetic Complexity: The synthesis of such a compound involves multiple steps and careful selection of reagents, emphasizing the creativity required in organic synthesis. Chemistry students can appreciate the strategic planning necessary to construct the desired molecule from simpler precursors.
  • Structural Diversity: The presence of a naphthyl group in the structure contributes to its unique characteristics, including enhanced lipophilicity, which can alter the compound's interaction with biological membranes and affect its pharmacokinetics.
  • Potential therapeutic applications: Given its structural components, this molecule could be investigated for use in treating various disorders, including those related to mood and anxiety, which may reflect the growing interest in developing innovative therapeutic agents.
  • Perspective on Drug Discovery: Understanding such complex compounds helps students develop a deeper appreciation for the challenges and innovations in drug discovery and the intricate relationship between molecular structure and biological activity. As renowned chemist Linus Pauling once said, “The best way to have a good idea is to have a lot of ideas.” This is especially true in medicinal chemistry.

In conclusion, delving into the world of 2-[2-[ethyl(methyl)amino]ethyl]-3-methyl-2-(1-naphthyl)butanenitrile opens up discussions about the synergy between structure and function in drug design, emphasizing the importance of multidisciplinary knowledge in chemistry and pharmacology.

Synonyms
BRN 2148335
2809-60-1
alpha-(2-(N-Ethyl-N-methylamino)ethyl)-alpha-isopropyl-1-naphthaleneacetonitrile
1-Naphthaleneacetonitrile, alpha-(2-(N-ethyl-N-methylamino)ethyl)-alpha-isopropyl-
DTXSID70950826
2-{2-[ETHYL(METHYL)AMINO]ETHYL}-3-METHYL-2-(NAPHTHALEN-1-YL)BUTANENITRILE