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2-(2-fluoroethoxy)ethanol

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Identification
Molecular formula
C4H9FO2
CAS number
362-13-4
IUPAC name
2-(2-fluoroethoxy)ethanol
State
State

At room temperature, 2-(2-fluoroethoxy)ethanol is in the liquid state. It is a volatile compound and should be handled with care to prevent inhalation exposure and skin contact. The compound's volatility and hygroscopic nature require it to be stored in airtight containers to maintain purity.

Melting point (Celsius)
-29.00
Melting point (Kelvin)
244.15
Boiling point (Celsius)
156.60
Boiling point (Kelvin)
429.75
General information
Molecular weight
108.12g/mol
Molar mass
108.1160g/mol
Density
1.1096g/cm3
Appearence

2-(2-Fluoroethoxy)ethanol is a colorless liquid. It has a slightly sweet odor, typical of many glycol ethers. Like other glycol ethers, it is hygroscopic and hence, will absorb moisture from the environment. Due to its ether and alcohol functional groups, it can participate in hydrogen bonding, making it miscible with water and many organic solvents.

Comment on solubility

Solubility of 2-(2-fluoroethoxy)ethanol

2-(2-fluoroethoxy)ethanol, with its intriguing structure, exhibits notable solubility characteristics that are essential for its potential applications. In general, the solubility of this compound can be described as:

  • Highly soluble in water: The presence of the hydroxyl (-OH) group contributes to its ability to form hydrogen bonds with water molecules, leading to increased solubility.
  • Good solubility in organic solvents: Compounds like ethanol, methanol, and acetone can dissolve 2-(2-fluoroethoxy)ethanol effectively due to the compound's hydrophilic and hydrophobic balance.
  • Influence of the fluorine atom: The fluorine substituent can enhance the polar character, which may further influence interactions with solvents.

As a rule of thumb, it is important to consider that solubility can be significantly affected by temperature and the presence of other solutes. In summary, 2-(2-fluoroethoxy)ethanol's solubility profile makes it a versatile compound for various chemical applications.

Interesting facts

Interesting Facts about 2-(2-fluoroethoxy)ethanol

2-(2-fluoroethoxy)ethanol, often abbreviated as FE, is a fascinating compound that beckons the attention of chemists and researchers alike. Its unique structure possesses a fluoroalkyl group, which imparts distinct properties and makes it a subject of interest in various applications.

Key Characteristics

  • Fluorine's Influence: The presence of fluorine in the molecule enhances its chemical stability and lipophilicity, affecting its interactions with biological systems and potentially leading to pharmaceutical applications.
  • Versatile Solvent: 2-(2-fluoroethoxy)ethanol can function as a solvent in many organic reactions, making it invaluable in synthetic organic chemistry.
  • Potential Pharmaceutical Uses: It shows promise in drug formulation due to its ability to modify the solubility and permeability of compounds.

Applications

This compound possesses a diverse range of applications, including:

  • Synthesis of fluorinated compounds: Its unique structure allows it to be a key reagent in the synthesis of various fluorinated organic compounds.
  • Coatings and treatments: The compound can be integrated into formulations for coatings, potentially enhancing properties such as water resistance and durability.
  • Research in material science: It is explored for its use in developing new materials that require specific chemical properties.

Conclusion

In summary, 2-(2-fluoroethoxy)ethanol is more than just a chemical formula; it stands at the intersection of synthetic chemistry, material science, and pharmaceutical research. As scientists continue to explore its applications, it holds the potential to unlock new innovations in various fields.

Synonyms
2-(2-fluoroethoxy)ethanol
373-22-8
2-(2-fluoroethoxy)ethan-1-ol
Ethanol, 2-(2-fluoroethoxy)-
ETHANOL, 2-(beta-FLUOROETHOXY)-
MFCD01727880
2-(beta-Fluoroethoxy)ethanol
2-Fluoro-2'-hydroxydiethyl ether
BRN 1733453
C4H9FO2
AI3-50937
SCHEMBL92157
4-01-00-02378 (Beilstein Handbook Reference)
DTXSID50190748
AKOS022504363
AT25497
ETHANOL, 2-(?-FLUOROETHOXY)-
NS-01006
CS-0199113
EN300-4293768
839-422-2