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2-[(2-Fluorophenyl)methylene]propanedinitrile

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Identification
Molecular formula
C10H5FN2
CAS number
1208-37-3
IUPAC name
2-[(2-fluorophenyl)methylene]propanedinitrile
State
State

Solid at room temperature.

This compound remains stable under normal conditions and is typically stored as a solid to prevent any degradation through contact with moisture or exposure to air.

Melting point (Celsius)
71.00
Melting point (Kelvin)
344.00
Boiling point (Celsius)
399.70
Boiling point (Kelvin)
672.80
General information
Molecular weight
159.15g/mol
Molar mass
159.1520g/mol
Density
1.1860g/cm3
Appearence

This compound appears as a pale yellow crystalline solid. It can also manifest as an off-white powder when purified and dry. It is characterized by a distinct aromatic odor.

Comment on solubility

Solubility of 2-[(2-fluorophenyl)methylene]propanedinitrile

2-[(2-fluorophenyl)methylene]propanedinitrile exhibits interesting solubility characteristics that are influenced by its chemical structure. Understanding the solubility behavior is crucial for various applications, especially in organic chemistry. Here are some key points to consider:

  • Polar vs. Nonpolar: This compound is largely nonpolar due to its long hydrocarbon chain and the presence of the nitrile groups. As a result, it tends to have limited solubility in polar solvents such as water.
  • Solvent Compatibility: However, it displays better solubility in nonpolar solvents or organic solvents, such as:
    • Hexane
    • Toluene
    • Chloroform
  • Temperature Influence: Solubility can also be influenced by temperature, with many compounds, including this one, having increased solubility at elevated temperatures.
  • Applications: Due to its solubility profile, 2-[(2-fluorophenyl)methylene]propanedinitrile can be effectively utilized in various organic reactions and synthesis pathways.

In summary, the solubility of 2-[(2-fluorophenyl)methylene]propanedinitrile is characterized by its preferential solubility in nonpolar solvents, making it essential to consider these properties when working with the compound in practical applications.

Interesting facts

Interesting Facts about 2-[(2-fluorophenyl)methylene]propanedinitrile

2-[(2-fluorophenyl)methylene]propanedinitrile is a fascinating compound that showcases the intricate relationships between molecular structure and reactivity. Here are some intriguing points that highlight its significance:

  • Functional Groups: This compound contains both a nitrile and a methylene group, which allows it to exhibit unique chemical behavior. These functional groups often participate in various types of reactions, including nucleophilic addition and condensation reactions.
  • Fluorine's Role: The presence of the fluorine atom in the phenyl ring markedly influences the compound’s chemical properties. Fluorine is known for its electronegativity, which can affect reactivity, solubility, and even the compound's interactions with biological systems.
  • Synthesis and Applications: The synthesis of 2-[(2-fluorophenyl)methylene]propanedinitrile can be achieved through various synthetic pathways, making it a valuable intermediate in organic synthesis. Compounds of this nature are often used in pharmaceuticals and agrochemicals, owing to their potential biological activity.
  • Research Interest: Researchers are particularly interested in compounds like this one due to their ability to act as potential inhibitors in biological systems. Studies have shown that certain nitrile-containing compounds exhibit anti-cancer and anti-inflammatory properties.
  • Versatile Chemistry: The versatility of this compound allows for various derivatizations, which can lead to the creation of novel materials with tailored properties for specific applications in material science and medicinal chemistry.

In summary, 2-[(2-fluorophenyl)methylene]propanedinitrile is not just a simple chemical entity but a compound that holds promise in medicinal chemistry and materials science. Its unique structure and the influence of the fluorine atom open potential pathways for innovative research and applications.

Synonyms
2698-43-3
2-[(2-fluorophenyl)methylidene]propanedinitrile
MALONONITRILE, (o-FLUOROBENZYLIDENE)-
2-Fluorobenzylidenemalononitrile
2-(2-Fluorobenzylidene)malononitrile
2-FLUOROBENZALMALONONITRILE
NSC637334
2-(2-Fluoro-benzylidene)-malononitrile
BRN 2613882
o-fluorobenzylidenemalononitrile
SCHEMBL3369090
DTXSID40181483
AKOS002951720
NSC-637334
2-(2-Fluorobenzylidene)malononitrile #
Benzene, 1-fluoro-2(2,2-dicyanoethenyl)
CS-0328168
2-[(2-fluorophenyl)methylene]propanedinitrile
6K-019
F3351-0490