Skip to main content

Flugestone acetate

ADVERTISEMENT
Identification
Molecular formula
C21H29FO4
CAS number
2529-45-5
IUPAC name
2-[(2-fluorophenyl)methyl]guanidine
State
State

At room temperature, flugestone acetate exists as a solid.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
258.65
Boiling point (Kelvin)
531.80
General information
Molecular weight
401.45g/mol
Molar mass
401.4540g/mol
Density
1.3300g/cm3
Appearence

Flugestone acetate is typically a white to off-white crystalline powder. It may be available in solid tablet form or as a fine amorphous powder, and it is slightly soluble in water.

Comment on solubility

Solubility of 2-[(2-fluorophenyl)methyl]guanidine

2-[(2-fluorophenyl)methyl]guanidine is a compound that displays interesting solubility characteristics, which can be attributed to its structural properties. Understanding its solubility can be invaluable for various applications, including pharmaceuticals and chemical synthesis.

  • Polar Nature: The presence of the guanidine functional group contributes to the polarity of the molecule, which may enhance its solubility in polar solvents, particularly water.
  • Aromatic Ring: The 2-fluorophenyl group, while increasing hydrophobic interactions due to its aromatic nature, may limit solubility in water but could enhance solubility in organic solvents.
  • Hydrogen Bonding: The ability of the guanidine moiety to form hydrogen bonds can facilitate interactions with solvent molecules, potentially increasing solubility in aqueous environments.
  • Temperature Dependency: Like many compounds, the solubility of 2-[(2-fluorophenyl)methyl]guanidine may increase with temperature, which is a common phenomenon in many organic compounds.

In applications, it is often crucial to determine the solubility of this compound in various solvents to predict its behavior in biological systems or during chemical reactions. Therefore, while 2-[(2-fluorophenyl)methyl]guanidine might show good solubility in certain conditions, the overall characteristics can be varied based on the solvent and environmental conditions involved.

Interesting facts

Interesting Facts about 2-[(2-fluorophenyl)methyl]guanidine

2-[(2-fluorophenyl)methyl]guanidine is a fascinating compound that has gained attention in the field of medicinal chemistry due to its unique properties and potential applications. Here are some intriguing aspects worth noting:

  • Structure and Composition: The compound features a guanidine backbone, which is known for its basic properties. The incorporation of a fluorophenyl group enhances its lipophilicity and may influence its biological activity.
  • Biological Activity: Compounds similar to 2-[(2-fluorophenyl)methyl]guanidine have been studied for their potential use as pharmaceuticals, particularly in the areas of anti-inflammatory and antitumor therapies.
  • Role of Fluorine: The presence of the fluorine atom in the fluorophenyl moiety can significantly impact the drug's pharmacokinetics and pharmacodynamics, affecting how the compound interacts with biological targets.
  • Synthetic Routes: Developing synthetic pathways for this compound may involve a variety of techniques in organic chemistry, such as substitution reactions and coupling reactions to achieve the desired structure.
  • Research Potential: Given its unique structure, 2-[(2-fluorophenyl)methyl]guanidine may serve as a lead compound for generating a series of analogs that could enhance its efficacy or selectivity for particular targets.

The exploration of 2-[(2-fluorophenyl)methyl]guanidine exemplifies how the integration of different chemical functionalities can lead to promising new molecules in the realm of drug discovery. As research continues, this compound may reveal even more exciting possibilities in the field of therapeutic agents.

Synonyms
704-98-3
GUANIDINE, (o-FLUOROBENZYL)-
(o-Fluorobenzyl)guanidine
BRN 2832334
DTXSID70220672
DTXCID00143163
1-(2-Fluorobenzyl)guanidine
(2-Fluorobenzyl)guanidine
N-[(2-FLUOROPHENYL)METHYL]GUANIDINE
2-[(2-fluorophenyl)methyl]guanidine
N-(2-fluorobenzyl)guanidine
SCHEMBL10310299
MFCD01724092
AKOS009145615
N-(2-Fluorobenzyl)guanidine; >90%
SY340560
EN300-1256349