Skip to main content

Nitrofurantoin

ADVERTISEMENT
Identification
Molecular formula
C8H6N4O5
CAS number
67-20-9
IUPAC name
2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide
State
State

Nitrofurantoin is a solid at room temperature. It typically comes in the form of a crystalline powder.

Melting point (Celsius)
276.00
Melting point (Kelvin)
549.15
Boiling point (Celsius)
577.00
Boiling point (Kelvin)
850.15
General information
Molecular weight
238.17g/mol
Molar mass
238.1560g/mol
Density
1.6760g/cm3
Appearence

Nitrofurantoin appears as a yellow crystalline solid. The compound is often supplied in a crystalline powder form.

Comment on solubility

Solubility of 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide

The solubility of 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide exhibits intriguing characteristics due to its chemical composition. Understanding its solubility is essential for applications in pharmaceutical and chemical industries.

Factors Influencing Solubility

  • Molecular Structure: The presence of multiple aromatic rings contributes to hydrophobic interactions, potentially resulting in low solubility in polar solvents.
  • Functional Groups: The amide functional group can enhance solubility in water via hydrogen bonding, whereas nitro groups might introduce polarity changes.
  • pH Sensitivity: The solubility may vary significantly with pH, affecting the ionization of the compound.

As a result of these factors, 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide may demonstrate:

  1. Moderate solubility in organic solvents such as DMSO and ethanol.
  2. Limited solubility in water, which can be attributed to its hydrophobic furan rings.

In conclusion, the solubility profile of this compound is multifaceted, highlighting a delicate balance between hydrophilic and hydrophobic characteristics, influenced by its unique structure.

Interesting facts

Interesting Facts about 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide

This fascinating compound, known as 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide, belongs to a unique class of organic molecules that exhibit a rich tapestry of functional groups and properties. Its intriguing structure features two furan rings, which contribute both to its aromatic nature and potential reactivity. Here are some noteworthy points:

  • Dual Furan Structure: The presence of two furyl groups imbues the compound with interesting electronic properties, enhancing its ability to participate in various chemical reactions.
  • Potential Applications: Compounds with similar structures have been studied extensively for their potential in pharmaceuticals and agrochemicals. This suggests that 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide may also hold therapeutic or industrial significance.
  • Biological Activity: Research indicates that furan-containing compounds can exhibit a range of biological activities, including antimicrobial and anticancer properties, making this compound a candidate for future investigations.
  • Reactivity and Synthesis: The unsaturated amide functional group in the compound may participate in nucleophilic addition reactions, which are fundamental in organic synthesis, providing pathways to more complex molecules.

As noted by chemists in the field, “Compounds like 2-(2-furyl)-3-(5-nitro-2-furyl)prop-2-enamide are crucial in bridging the gap between synthetic chemistry and biotechnology.” This statement underscores the importance of such compounds in both academic research and applied sciences.

Overall, the fascinating structural features and potential applications of this compound make it an exciting topic of study in the realms of organic chemistry and materials science. With ongoing research, who knows what interesting properties yet remain to be discovered!

Synonyms
2-(furan-2-yl)-3-(5-nitrofuran-2-yl)prop-2-enamide
2-(Furan-2-yl)-3-(5-nitrofuran-2-yl)acrylamide
SCHEMBL106826
DTXSID40859832
2-(2-furyl)-3-(5-nitrofuryl)-acrylamide