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Brompheniramine

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Identification
Molecular formula
C16H19BrN2
CAS number
86-22-6
IUPAC name
2-[[2-hydroxy-2-phenyl-2-(2-thienyl)acetyl]-methyl-amino]ethyl-dimethyl-(2-phenylethyl)ammonium;bromide
State
State

Brompheniramine is in a solid state at room temperature. It is typically found as a crystalline powder, which is stable and can be readily handled under normal conditions.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
435.33g/mol
Molar mass
435.3280g/mol
Density
1.3704g/cm3
Appearence

Brompheniramine is typically a white to off-white crystalline powder. Its appearance can be fine crystalline or as larger crystals, and it is generally odorless or may have a faint characteristic odor.

Comment on solubility

Solubility of 2-[[2-hydroxy-2-phenyl-2-(2-thienyl)acetyl]-methyl-amino]ethyl-dimethyl-(2-phenylethyl)ammonium; bromide

The solubility of this compound, often recognized by its complex structure, is influenced by several factors, contributing to its behavior in different solvents. Understanding its solubility can be framed around the following aspects:

  • Polarity: The presence of phenyl and thienyl groups in the structure suggests that this compound may exhibit both polar and non-polar characteristics, potentially limiting its solubility in strictly non-polar solvents.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents, particularly water, due to its ammonium bromide component, which typically favors solubility in aqueous environments.
  • Temperature Influence: Solubility can increase with temperature; thus, higher temperatures might enhance its dissolution in suitable solvents.
  • Formulation Factors: The overall solubility can also be affected by the pH of the solution, which may alter the ionization states of the compound, thus impacting its solubility profile.

To summarize, while this compound may show limited solubility in non-polar solvents, it is expected to be more soluble in polar solvents, especially under conditions of increased temperature and optimal pH. As always, experimental data should be consulted for exact solubility values in specific solvents.

Interesting facts

Interesting Facts about 2-[[2-Hydroxy-2-phenyl-2-(2-thienyl)acetyl]-methyl-amino]ethyl-dimethyl-(2-phenylethyl)ammonium; Bromide

This compound presents a fascinating fusion of organic chemistry and medicinal applications. It belongs to a class of compounds known as quaternary ammonium salts, which are often utilized for their unique properties in various fields. Here are some intriguing points to note:

  • Biological Activity: Many quaternary ammonium compounds exhibit significant biological activity, making them valuable in pharmacology. This compound's structure may suggest potential antimicrobial or antiseptic properties.
  • Structural Complexity: The presence of multiple functional groups, including hydroxy, phenyl, and thienyl moieties, indicates a rich chemical landscape. Such complexity often leads to diverse reactivity patterns in synthesis and interaction with biological systems.
  • Applications in Drug Delivery: Compounds like this one can be pivotal in drug delivery systems because of their ability to interact with biological membranes, enhancing the solubility and absorption of drugs.
  • Understanding Structure-Activity Relationships: Analyzing how modifications in this compound's structure affect its biological activity provides valuable insights into medicinal chemistry and helps guide future drug design.

As we delve deeper into the potential applications of this compound, it’s clear that its intricate design is not just a theoretical curiosity but a substance with real-world implications for health and medicine. As Dr. Jane Goodall once said, "What you do makes a difference, and you have to decide what kind of difference you want to make." The study of compounds like this can certainly make a significant difference in the world of chemistry and beyond.

Synonyms
FC 111
26058-51-5
Ammonium, dimethyl(2-(N-methyl-alpha-2-thienylmandelamido)ethyl)phenethyl-, bromide
Ammonium, dimethyl(2-(alpha-hydroxy-N-methyl-alpha-phenyl-2-thiopheneacetamido)ethyl)phenethyl-, bromide
RefChem:319305
DTXSID80948936
2-{[Hydroxy(phenyl)(thiophen-2-yl)acetyl](methyl)amino}-N,N-dimethyl-N-(2-phenylethyl)ethan-1-aminium bromide