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Phenylephrine

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Identification
Molecular formula
C9H13NO2
CAS number
59-42-7
IUPAC name
2-(2-hydroxy-2-phenyl-ethyl)guanidine
State
State
At room temperature, phenylephrine is typically in the form of a solid. As a medicine, it is frequently prepared as a hydrochloride salt, which is also solid at room temperature. Phenylephrine hydrochloride is used in solutions and tablets.
Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
256.00
Boiling point (Kelvin)
529.15
General information
Molecular weight
167.21g/mol
Molar mass
167.2060g/mol
Density
1.2960g/cm3
Appearence
Phenylephrine appears as a white or almost white powder. It is odorless and generally has a bitter taste. In practical applications, phenylephrine is often supplied in its hydrochloride form, which also appears as a crystalline powder.
Comment on solubility

Solubility of 2-(2-hydroxy-2-phenyl-ethyl)guanidine

The solubility of 2-(2-hydroxy-2-phenyl-ethyl)guanidine is influenced by several factors, making it an interesting compound to study. Generally, this compound is expected to exhibit moderate to good solubility in polar solvents. Here are some key points to consider:

  • Polarity: Due to the presence of the hydroxyl group (-OH) and the guanidine functional group, 2-(2-hydroxy-2-phenyl-ethyl)guanidine can engage in hydrogen bonding, enhancing its solubility in water and other polar solvents.
  • Solvent Interaction: It tends to dissolve well in solvents such as ethanol and methanol, which can interact favorably with the compound's polar functional groups.
  • Concentration Dependence: As with many organic compounds, its solubility may vary with concentration; at higher concentrations, solubility limitations might become apparent.
  • Temperature Effects: Increased temperature often enhances solubility for many compounds, and 2-(2-hydroxy-2-phenyl-ethyl)guanidine may exhibit similar behavior.

In summary, while specific solubility data may vary, it is clear that the structure of 2-(2-hydroxy-2-phenyl-ethyl)guanidine plays a significant role in its solubility characteristics, particularly in polar environments where it can effectively engage in solvation processes.

Interesting facts

Interesting Facts about 2-(2-Hydroxy-2-phenyl-ethyl)guanidine

2-(2-Hydroxy-2-phenyl-ethyl)guanidine is a fascinating compound that has drawn interest in pharmaceutical chemistry due to its potential as a therapeutic agent. Here are some noteworthy aspects of this compound:

  • Structure & Functionality: This compound features a guanidine group, known for its biological activity, which has been studied in various medicinal contexts. The presence of the hydroxy and phenyl groups enhances its interaction with biological systems.
  • Biological Relevance: Compounds with guanidine functionalities have been explored for their inhibitory effects on enzymes and their roles in regulating blood sugar levels, making them significant in diabetes research.
  • Mechanism of Action: The guanidine moiety may mimic or influence biochemical pathways, potentially acting as a substrate or inhibitor in various reactions, which is pivotal in drug design.
  • Synthesis: The synthetic routes to create this compound often involve multi-step organic reactions, showcasing valuable techniques in organic synthesis and the importance of reaction conditions in yields and selectivity.
  • Research Potential: Ongoing studies are examining the compound's effects on cellular signaling pathways, which could pave the way for new treatments in metabolic disorders.

According to one researcher, "Exploration of compounds like 2-(2-hydroxy-2-phenyl-ethyl)guanidine offers a window into the development of novel therapeutic strategies that can revolutionize treatment paradigms." This statement underscores the importance of such compounds in the ever-evolving field of medicinal chemistry.

In summary, 2-(2-hydroxy-2-phenyl-ethyl)guanidine not only exemplifies the intricate relationship between molecular structure and biological activity but also continues to be a subject of extensive research with promising implications in drug discovery and development.

Synonyms
beta-hydroxy-phenethylguanidine
SCHEMBL3921879
SCHEMBL3921881
AKOS011645141