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N-acetylanthranilic acid

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Identification
Molecular formula
C9H9NO3
CAS number
89-52-1
IUPAC name
2-[(2-hydroxybenzoyl)amino]acetic acid
State
State
This compound is a solid at room temperature.
Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
181.17g/mol
Molar mass
181.1650g/mol
Density
1.4650g/cm3
Appearence

N-acetylanthranilic acid typically appears as a white to off-white crystalline solid. The solid may form as a powder or small crystalline fragments depending on the method of purification and crystallization used.

Comment on solubility

Solubility of 2-[(2-hydroxybenzoyl)amino]acetic acid

2-[(2-hydroxybenzoyl)amino]acetic acid, often categorized among amino acids, displays a fascinating profile when it comes to solubility. Understanding its solubility properties involves a few key points:

  • Polarity: This compound possesses polar functional groups, which often enhances its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) and amino (-NH2) groups promotes strong intermolecular hydrogen bonds, potentially increasing solubility in aqueous solutions.
  • pH Dependence: The solubility can also be influenced by pH levels, as ionization of the carboxylic acid group can enhance solubility in basic conditions.
  • Solvent Choice: Additionally, this compound may show variable solubility in organic solvents, depending on their polarity.

To rephrase the conclusion, one might say, "the solubility of 2-[(2-hydroxybenzoyl)amino]acetic acid is a result of its molecular structure that facilitates interaction with solvent molecules through hydrogen bonding and pH variation."

Overall, this compound demonstrates significant solubility in various solvents, particularly in polar environments, making it a versatile component in chemical applications.

Interesting facts

Exploring 2-[(2-hydroxybenzoyl)amino]acetic Acid

2-[(2-hydroxybenzoyl)amino]acetic acid, commonly referred to as an important derivative in the realm of amino acids, possesses considerable significance in both chemical research and practical applications. This compound is characterized by its unique structural features, which make it a subject of interest among chemists.

Key Features and Properties

  • Amino Acid Derivative: This compound is a derivative of glycine, indicating its foundational role in a variety of biochemical processes.
  • Functional Groups: The presence of both hydroxyl and carbonyl groups lends this compound unique reactivity profiles, making it a potential candidate for various synthetic pathways.
  • Pharmaceutical Potential: Compounds structurally related to 2-[(2-hydroxybenzoyl)amino]acetic acid may exhibit biological activity, paving the way for new drug development.

Furthermore, its role as a potential chelating agent opens the door for applications in the field of medicinal chemistry, particularly in the development of treatments involving metal ion interactions. This aspect is often highlighted in studies aiming to enhance drug efficacy and specificity.

Fun Fact

According to *chemical literature*, “the interplay between amino acids and their derivatives can lead to innovative solutions in pharmaceuticals, improving targeted therapies and minimizing side effects.” This illustrates the growing importance of studying compounds like 2-[(2-hydroxybenzoyl)amino]acetic acid!

As ongoing research continues to unveil more about this intriguing compound, it stands as a testament to the incredible diversity and potential of chemical compounds in advancing science and medicine.

Synonyms
Salicyluric acid
487-54-7
Glycine, N-(2-hydroxybenzoyl)-
N-Salicyloylglycine
Salicyloylglycine
o-Hydroxyhippuric acid
NSC-87566
2-[(2-hydroxybenzoyl)amino]acetic acid
2-[(2-hydroxyphenyl)formamido]acetic acid
N-(2-Hydroxybenzoyl)-glycine
5BR3P7J05U
CHEBI:9008
Salicyluric Acid (50-80-%)
NSC-524135
(2-hydroxybenzamido)acetic acid
2-((2-hydroxybenzoyl)amino)acetic acid
2-((2-hydroxyphenyl)formamido)acetic acid
Glycine, N-(2-hydroxybenzoyl)-(9CI)
2-Hydroxyhippuric acid
Salicylurate
2-hydroxy hippuric acid
N-(2-Hydroxybenzoyl)glycine
2-(2-hydroxybenzamido)acetic acid
N-o-Hydroxybenzoylglycine
2-Hydroxybenzoylglycine
HIPPURIC ACID, o-HYDROXY-
(2-Hydroxybenzoyl)glycine
NSC 524135
NSC87566
ortho-Hydroxyhippuric acid
[(2-Hydroxybenzoyl)amino]acetic acid
CHEMBL586
((2-hydroxybenzoyl)amino)acetic acid
o-Hydroxyhippurate
2-Hydroxyhippurate
WLN: QV1MVR BQ
ortho-Hydroxyhippurate
o-hydroxy-hippuric acid
Glycine, N-salicyloyl-
2-Hydroxybenzoylaminoacetic acid
EINECS 207-661-6
NSC 87566
BRN 2213833
UNII-5BR3P7J05U
Salicylursaure
o-hydroxy-Hippurate
MFCD00002695
2-hydroxybenzoylaminoacetate
Hippuric acid, 2-hydroxy-
NCIStruc1_000217
NCIStruc2_000217
Salicyluric acid (Standard)
Oprea1_189845
Oprea1_844373
4-10-00-00172 (Beilstein Handbook Reference)
SCHEMBL570541
[(2-Hydroxybenzoyl)amino]acetate
2-(2-hydroxybenzamido)aceticacid
DTXSID70197592
NCI87566
BDBM50328021
CCG-36270
NCGC00013916
NSC524135
(2-Hydroxy-benzoylamino)-acetic acid
(2-hydroxybenzoyl amino)-acetic acid
(2-hydroxy-benzoyl amino)-acetic acid
AKOS000126862
FH24019
HY-113295R
PS-5117
NCGC00013916-02
NCGC00097025-01
acetic acid, 2-(2-hydroxybenzoylamino)-
NCI60_041936
o-Hydroxyhippuric acid, analytical standard
HY-113295
2-Hydroxyhippuric acid (BZ(2-OH)-Gly-OH)
CS-0059539
NS00006840
C07588
EN300-252801
G12038
Q2214314
4DD455E5-CFA8-4AFD-B0A3-267800311FA5
N-(2-Hydroxybenzoyl)glycine;o-Hydroxy-hippuric acid;Salicyluric acid
InChI=1/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13